Recombinant Stanniocalcin 2 (STC2) | MyBioSource MBS2010496 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Stanniocalcin 2 (STC2)

catalog :

MBS2010496

quantity :

0.01 mg

price :

195 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2010496

products type :

Recombinant Protein

products full name :

Recombinant Stanniocalcin 2 (STC2)

products short name :

Stanniocalcin 2 (STC2)

other names :

stanniocalcin-2; Stanniocalcin-2; stanniocalcin-2; STC-related protein; stanniocalcin-related protein; stanniocalcin 2; Stanniocalcin-related protein

products gene name :

STC2

other gene names :

STC2; STC2; STC-2; STCRP; STC-2; STC-related protein; STCRP

uniprot entry name :

STC2_HUMAN

host :

E Coli

sequence length :

302

sequence :

The target protein is fused with N-terminal His-Tag, its sequence is listed below. MGHHHHHHSGSEF-IQHCLVNA GDVGCGVFEC FENNSCEIRG LHGICMTFLH NAGKFDAQGK SFIKDALKCK AHALRHRFGC ISRKCPAIRE MVSQLQRECY LKHDLCAAAQ ENTRVIVEMI HFKDLLLHEP YVDLVNLLLT CGEEVKEAIT HSVQVQCEQN WGSLCSILSF CTSAIQKPPT APPERQPQVD RTKLSRAHHG EAGHHLPEPS SRETGRGAKG ERGSKSHPNA HARGRVGGLG AQGPSGSSEW EDEQ

purity :

> 95%

form :

Supplied as lyophilized form in 20mM Tris, 500mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.

storage stability :

Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

tested application :

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

app notes :

(May be suitable for use in other assays to be determined by the end user.)

other info1 :

Organism: Homo sapiens (Human). Expression System: Prokaryotic expression. Residues: Ile53~Gln294 (Accession # O76061) with N-terminal His-Tag. Predicted isoelectric point: 7.1

other info2 :

Endotoxin Level: <1.0EU per 1ug (determined by the LAL method). Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

products description :

About the Marker: Effective Size Range: 10kDa to 70kDa. Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa. Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy. Ready-to-use: No need to heat, dilute or add reducing agents before use.

ncbi gi num :

4507267

ncbi acc num :

NP_003705.1

ncbi gb acc num :

NM_003714.2

uniprot acc num :

O76061

ncbi mol weight :

28.2kDa

ncbi summary :

This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. [provided by RefSeq, Jul 2008]

uniprot summary :

STC2: a secreted protein that has an anti-hypocalcemic action on calcium and phosphate homeostasis. Expressed in a variety of tissues including muscle, heart, pancreas, kidney, spleen, prostate, small intestine, colon and peripheral blood leucocytes. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 5q35.1. Cellular Component: Golgi apparatus; extracellular space; endoplasmic reticulum; perinuclear region of cytoplasm. Molecular Function: protein homodimerization activity; enzyme binding; hormone activity; heme binding. Biological Process: cellular calcium ion homeostasis; response to peptide hormone stimulus; negative regulation of multicellular organism growth; response to vitamin D; unfolded protein response; decidualization; response to oxidative stress; regulation of hormone biosynthetic process; embryo implantation

size1 :

0.01 mg

price1 :

195 USD

size2 :

0.05 mg

price2 :

420

size3 :

0.1 mg

price3 :

650

more info or order :

MyBioSource product webpage