product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Desmoglein 3 (DSG3)
catalog :
MBS2010322
quantity :
0.01 mg
price :
175 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2010322
products type :
Recombinant Protein
products full name :
Recombinant Desmoglein 3 (DSG3)
products short name :
Desmoglein 3 (DSG3)
other names :
desmoglein-3 preproprotein; Desmoglein-3; desmoglein-3; cadherin family member 6; pemphigus vulgaris antigen; 130-kD pemphigus vulgaris antigen; 130 kDa pemphigus vulgaris antigen; desmoglein 3; 130 kDa pemphigus vulgaris antigen; PVA; Cadherin family member 6
products gene name :
DSG3
other gene names :
DSG3; DSG3; PVA; CDHF6; CDHF6; PVA
uniprot entry name :
DSG3_HUMAN
host :
E Coli
sequence length :
999
sequence :
EIS LGVDGEGKEV QPPSKDSGYG IESCGHPIEV QQTGFVKCQT LSGSQGASAL STSGSVQPAV SIPDPLQHGN YLVTETYSAS GSLVQPSTAG FDPLLTQNVI VTERVICPIS SVPGNLAGPT QLRGSHTMLC TEDPCSRLI
purity :
> 92%
form :
Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
storage stability :
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
tested application :
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
other info1 :
Organism: Homo sapiens (Human). Expression System: Prokaryotic expression. Residues: Glu858~Ile999 (Accession # P32926) with two N-terminal Tags, His-tag and GST-tag
other info2 :
Endotoxin Level: <1.0EU per 1ug (determined by the LAL method). Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4. Predicted isoelectric point: 5.7
products description :
About the Marker: Effective Size Range: 10kDa to 70kDa. Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa. Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy. Ready-to-use: No need to heat, dilute or add reducing agents before use.
ncbi gi num :
119964718
ncbi acc num :
NP_001935.2
ncbi gb acc num :
NM_001944.2
uniprot acc num :
P32926
ncbi mol weight :
46.6kDa
ncbi pathways :
Apoptosis Pathway (105648); Apoptotic Cleavage Of Cell Adhesion Proteins Pathway (105680); Apoptotic Cleavage Of Cellular Proteins Pathway (105678); Apoptotic Execution Phase Pathway (105677)
ncbi summary :
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. [provided by RefSeq, Jul 2008]
uniprot summary :
DSG3: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Protein type: Cell adhesion; Membrane protein, integral. Chromosomal Location of Human Ortholog: 18q12.1. Cellular Component: desmosome; plasma membrane; integral to membrane; cytosol. Molecular Function: calcium ion binding. Biological Process: apoptosis; homophilic cell adhesion; cell structure disassembly during apoptosis
size1 :
0.01 mg
price1 :
175 USD
size2 :
0.05 mg
price2 :
370
size3 :
0.1 mg
price3 :
575
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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