protein

Recombinant Apolipoprotein C2 (APOC2)

MBS2010311

0.01 mg

170 USD

Recombinant Protein

Recombinant Apolipoprotein C2 (APOC2)

Apolipoprotein C2 (APOC2)

apolipoprotein C-II; Apolipoprotein C-II; apolipoprotein C-II; apo-CII; apoC-II; apolipoprotein C2; apolipoprotein C-II; Apolipoprotein C2

APOC2

Apoc2; Apoc2; Apo-CII; ApoC-II

APOC2_MOUSE

E Coli

Mus musculus (Mouse)

97

The sequence of the target protein is listed below. ILMLGNEV QGNQEDDSGS LALLGTVQGS LLSYWTSAKE VAKDLYQKTY PISMDEKLRD MYSKSSAAMS TYAGIFTDQL LTLLRGE

> 95%

Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.

Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

Expression System: Prokaryotic expression. Residues: Ile13~Glu97 (Accession # Q05020) with two N-terminal Tags, His-tag and GST-tag. Subcellular Location: Secreted. Predicted isoelectric point: 5.7

Endotoxin Level: <1.0EU per 1ug (determined by the LAL method). Predicted Isoelectric Point: 41.3. Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

About the Marker: Effective Size Range: 10kDa to 70kDa. Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa. Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy. Ready-to-use: No need to heat, dilute or add reducing agents before use.

485050543

NP_001264873.1

NM_001277944.1

Q05020

41.3kDa

Disease Pathway (926229); Diseases Associated With Visual Transduction Pathway (926305); Retinoid Metabolism And Transport Pathway (926309); Signal Transduction Pathway (926897); Statin Pathway (198363); Visual Phototransduction Pathway (926308)

APOC2: Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B). It is an autosomal recessive trait characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. Belongs to the apolipoprotein C2 family. Protein type: Secreted; Secreted, signal peptide. Cellular Component: extracellular space; chylomicron; extracellular region. Molecular Function: protein homodimerization activity; phospholipase binding; lipase inhibitor activity; enzyme activator activity; lipid binding; phospholipase activator activity. Biological Process: positive regulation of fatty acid biosynthetic process; negative regulation of cholesterol transport; cholesterol efflux; lipid transport; phospholipid efflux; transport; lipoprotein transport; negative regulation of catalytic activity; positive regulation of lipoprotein lipase activity; negative regulation of receptor-mediated endocytosis; lipid metabolic process; negative regulation of lipid metabolic process; lipid catabolic process

0.01 mg

170 USD

0.05 mg

350

0.1 mg

545