catalog number :
MBS2010221
products type :
Recombinant Protein
products full name :
Recombinant Annexin A4 (ANXA4)
products short name :
Annexin A4 (ANXA4)
other names :
annexin A4; Annexin A4; annexin A4; annexin-4; annexin IV; annexin A4; Annexin IV; Annexin-4
products gene name :
ANXA4
other gene names :
Anxa4; Anxa4; AIV; Anx4; Xanx-4; AI265406; AW106930; Anx4
uniprot entry name :
ANXA4_MOUSE
sequence :
The sequence of the target protein is listed below. DAI IGI LAYRNTAQRQ EIRSAYKSTI GRDLIEDLKS ELSSNFEQVI LGLMTPTVLY DVQELRRAMK GAGTDEGCLI EILASRTPEE IRRINQTYQQ QYGRSLEEDI CSDTSFMFQR VLVSLSA
form :
Supplied as lyophilized form in 20mM Tris, 500mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
storage stability :
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
tested application :
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). (May be suitable for use in other assays to be determined by the end user.)
other info1 :
Organism: Mus musculus (Mouse). Expression System: Prokaryotic expression. Residues: Asp35~Ala157 (Accession # P97429) with N-terminal His-Tag
other info2 :
Endotoxin Level: <1.0EU per 1ug (determined by the LAL method). Reconstitution: Reconstitute in ddH2O. Predicted isoelectric point: 5.6
products description :
About the Marker: Effective Size Range: 10kDa to 70kDa. Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa. Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy. Ready-to-use: No need to heat, dilute or add reducing agents before use.
ncbi acc num :
NP_038499.2
ncbi gb acc num :
NM_013471.2
ncbi mol weight :
15.5kDa
ncbi pathways :
Prostaglandin Synthesis And Regulation Pathway (198286)
uniprot summary :
ANXA4: a calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion. Protein type: Calcium-binding; Lipid-binding. Cellular Component: nuclear membrane; cell surface; perinuclear region of cytoplasm; apical plasma membrane; cytoplasm; plasma membrane; vesicle membrane; nucleus. Molecular Function: identical protein binding; NF-kappaB binding; calcium-dependent phospholipid binding; calcium ion binding; calcium-dependent protein binding. Biological Process: regulation of transcription from RNA polymerase II promoter; inhibition of NF-kappaB transcription factor; kidney development