catalog number :
MBS2010176
products type :
Recombinant Protein
products full name :
Recombinant Kidney Injury Molecule 1 (Kim1)
products short name :
[Kidney Injury Molecule 1 (Kim1)]
other names :
[hepatitis A virus cellular receptor 1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1; kidney injury molecule 1; T-cell membrane protein 1; T-cell immunoglobulin mucin receptor 1; T-cell immunoglobulin mucin family member 1; T cell immunoglobin domain and mucin domain protein 1; hepatitis A virus cellular receptor 1; Kidney injury molecule 1; KIM-1; T-cell immunoglobulin and mucin domain-containing protein 1; TIMD-1; T-cell immunoglobulin mucin receptor 1; TIM; TIM-1; T-cell membrane protein 1]
products gene name :
[Kim1]
other gene names :
[HAVCR1; HAVCR1; TIM; KIM1; TIM1; HAVCR; KIM-1; TIM-1; TIMD1; TIMD-1; HAVCR-1; KIM1; TIM1; TIMD1; HAVcr-1; KIM-1; TIMD-1; TIM; TIM-1]
uniprot entry name :
HAVR1_HUMAN
form :
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
concentration :
200 ug/mL
storage stability :
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
tested application :
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). (May be suitable for use in other assays to be determined by the end user.)
image1 heading :
Sequence Information
image2 heading :
SDS-Page
image3 heading :
Testing Data
other info1 :
Organism Species: Homo sapiens (Human). Source: Prokaryotic expression. Residues: Ser21~Ala245 liked with DSSTTTTTTTTN . Tags: N-terminal His and GST Tag. Subcellular Location: Membrane. Traits: Freeze-dried powder
other info2 :
Predicted isoelectric point: 8.6. Predicted Molecular Mass: 55.1kDa. Accurate Molecular Mass: 55kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
ncbi acc num :
NP_001092884.1
ncbi gb acc num :
NM_001099414.1
ncbi summary :
The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4, 12 and 19. [provided by RefSeq, Apr 2015]
uniprot summary :
TIM-1: May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair. Belongs to the immunoglobulin superfamily. TIM family. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 5q33.2. Cellular Component: integral to membrane. Molecular Function: viral receptor activity. Biological Process: entry of virus into host cell. Disease: Ige Responsiveness, Atopic