catalog number :
MBS2010161
products type :
Recombinant Protein
products full name :
Recombinant Galectin 9 (GAL9)
products short name :
Galectin 9 (GAL9)
other names :
galectin-9; Galectin-9; galectin-9; UAT; gal-9; urate transporter/channel; 36 kDa beta-galactoside-binding lectin; Lectin galactose binding soluble 9 (Galectin-9); Lectin, galactose binding, soluble 9 (Galectin-9); lectin, galactoside-binding, soluble, 9; 36 kDa beta-galactoside-binding lectin; Urate transporter/channel
products gene name :
GAL9
other gene names :
Lgals9; Lgals9; Gal-9; UAT
uniprot entry name :
LEG9_RAT
sequence :
The target protein is fused with N-terminal His-Tag, its sequence is listed below. MGHHHHHHSGSEF-FTGI IQGGLQNGLQ ITLQGTVHPF PNRIAVNFQT GFSGNDIAFH FNPRFEEGGY VVCNTKQNGK WGPEERKMQM PFQKGMPFEL CFLVQRSEFK VMVNKNFFVQ YSHRVPYHLV DTISVSGCLH LSFINFQ
form :
Supplied as lyophilized form in 20mM Tris, 500mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
storage stability :
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
tested application :
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
other info1 :
Organism: Rattus norvegicus (Rat). Expression System: Prokaryotic expression. Residues: Phe17~Gln147 (Accession # P97840) with N-terminal His-Tag
other info2 :
Endotoxin Level: <1.0EU per 1ug (determined by the LAL method). Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4. Predicted isoelectric point: 8.5. USAGE:
Reconstitute in ddH2O.
products description :
About the Marker: Effective Size Range: 10kDa to 70kDa. Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa. Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy. Ready-to-use: No need to heat, dilute or add reducing agents before use.
ncbi acc num :
NP_037109.1
ncbi gb acc num :
NM_012977.1
ncbi mol weight :
16.5kDa
ncbi summary :
a highly selective urate transporter/channel [RGD, Feb 2006]
uniprot summary :
galectin-9: Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Unknown function. Cellular Component: cytoplasm; extracellular region. Molecular Function: signal transducer activity; carbohydrate binding. Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; ion transport; signal transduction