Recombinant Laminin Alpha 1 (LAMa1) | MyBioSource MBS2009836 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Laminin Alpha 1 (LAMa1)

catalog :

MBS2009836

quantity :

0.01 mg

price :

115 USD

more info or order :

MyBioSource product webpage

image

image 1 :

image 2 :

product information

catalog number :

MBS2009836

products type :

Recombinant Protein

products full name :

Recombinant Laminin Alpha 1 (LAMa1)

products short name :

[Laminin Alpha 1 (LAMa1)]

other names :

[laminin subunit alpha-1; Laminin subunit alpha-1; laminin subunit alpha-1; S-LAM alpha; laminin A chain; S-laminin subunit alpha; laminin-3 subunit alpha; laminin, alpha 1; Laminin A chain; Laminin-1 subunit alpha; Laminin-3 subunit alpha; S-laminin subunit alpha]

products gene name :

[LAMa1]

other gene names :

[LAMA1; LAMA1; LAMA; S-LAM-alpha; LAMA; S-LAM alpha]

uniprot entry name :

LAMA1_HUMAN

host :

E Coli

purity :

> 95%

concentration :

Original Concentration: 200 ug/mL

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

Positive Control, Immunogen, SDS-PAGE, WB. (May be suitable for use in other assays to be determined by the end user.)

image1 heading :

Sequence Information

image2 heading :

SDS-Page

other info1 :

Source: Prokaryotic expression. Organism Species: Homo sapiens (Human). Residues: Val2613~Phe2746. Tags: N-terminal His Tag. Subcellular Location: Secreted. Traits: Freeze-dried powder. Buffer formulation: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

other info2 :

Predicted isoelectric point: 6.0. Predicted Molecular Mass: 16.2kDa. Accurate Molecular Mass: 16kDa as determined by SDS-PAGE reducing conditions. USAGE: Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

products description :

About the Marker: Effective Size Range: 10kDa to 70kDa. Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa. Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy. Ready-to-use: No need to heat, dilute or add reducing agents before use.

ncbi gi num :

38788416

ncbi acc num :

NP_005550.2

ncbi gb acc num :

NM_005559.3

uniprot acc num :

P25391

ncbi pathways :

Alpha6-Beta4 Integrin Signaling Pathway (198807); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Axon Guidance Pathway (105688); Developmental Biology Pathway (477129); ECM Proteoglycans Pathway (833812); ECM-receptor Interaction Pathway (83068); ECM-receptor Interaction Pathway (479); Extracellular Matrix Organization Pathway (576262); Focal Adhesion Pathway (198795)

ncbi summary :

This gene encodes one of the alpha 1 subunits of laminin. The laminins are a family of extracellular matrix glycoproteins that have a heterotrimeric structure consisting of an alpha, beta and gamma chain. These proteins make up a major component of the basement membrane and have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Mutations in this gene may be associated with Poretti-Boltshauser syndrome. [provided by RefSeq, Sep 2014]

uniprot summary :

LAMA1: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide; Extracellular matrix. Chromosomal Location of Human Ortholog: 18p11.3. Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; laminin-3 complex; laminin-1 complex; extracellular region; basement membrane; intercellular junction. Molecular Function: protein binding; extracellular matrix structural constituent; glycosphingolipid binding; receptor binding. Biological Process: regulation of cell adhesion; axon guidance; extracellular matrix organization and biogenesis; cell surface receptor linked signal transduction; regulation of embryonic development; morphogenesis of an epithelial sheet; establishment of epithelial cell polarity; cell adhesion; regulation of cell migration. Disease: Poretti-boltshauser Syndrome

size1 :

0.01 mg

price1 :

115 USD

size2 :

0.05 mg

price2 :

200

size3 :

0.1 mg

price3 :

290

size4 :

0.2 mg

price4 :

360

size5 :

0.5 mg

price5 :

690

size6 :

1 mg

price6 :

1015

more info or order :

MyBioSource product webpage