product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Mesothelin (MSLN)
catalog :
MBS2009468
quantity :
0.01 mg
price :
165 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2009468
products type :
Recombinant Protein
products full name :
Recombinant Mesothelin (MSLN)
products short name :
Mesothelin (MSLN)
other names :
mesothelin isoform 1 preproprotein; Mesothelin; mesothelin; CAK1 antigen; megakaryocyte potentiating factor; soluble MPF mesothelin related protein; pre-pro-megakaryocyte-potentiating factor; mesothelin; CAK1 antigen; Pre-pro-megakaryocyte-potentiating factor
products gene name :
MSLN
other gene names :
MSLN; MSLN; MPF; SMRP; MPF; MPF
uniprot entry name :
MSLN_HUMAN
host :
E Coli
reactivity :
Homo sapiens (Human)
purity :
>92%
form :
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300.
storage stability :
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
tested application :
SDS-PAGE; WB; ELISA; IP; CoIP; ReporterAssays; Purification; Amine Reactive Labeling. (May be suitable for use in other assays to be determined by the end user.)
other info1 :
Tissue Specificity: Lung, Heart, Kidney. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus, Secreted. Expression System: Prokaryotic expression. Residues: Glu400~Leu615 with two N-terminal Tags, His-tag and GST-tag. Traits: Freeze-dried powder
other info2 :
Predicted isoelectric point: 5.2. Predicted Molecular Mass: 53.7kDa. Accurate Molecular Mass: 54kDa as determined by SDS-PAGE reducing conditions. Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4. Predicted isoelectric point: 5.7. Usage: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
ncbi gi num :
293651530
ncbi acc num :
NP_001170826.1
ncbi gb acc num :
NM_001177355.1
uniprot acc num :
Q13421
ncbi summary :
This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
uniprot summary :
MSLN: Membrane-anchored forms may play a role in cellular adhesion. Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer. Belongs to the mesothelin family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Cell adhesion; Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: Golgi apparatus; extracellular space; cell surface; membrane; plasma membrane. Molecular Function: protein binding. Biological Process: pancreas development; cell adhesion
size1 :
0.01 mg
price1 :
165 USD
size2 :
0.05 mg
price2 :
325
size3 :
0.1 mg
price3 :
505
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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