catalog number :
MBS2009201
products type :
Recombinant Protein
products full name :
Recombinant Laminin Beta 1 (LAMb1)
products short name :
[Laminin Beta 1 (LAMb1)]
other names :
[Laminin subunit beta-1; Laminin subunit beta-1; laminin subunit beta-1; laminin B1 chain; laminin B1 subunit 1; laminin-1 subunit beta; laminin-2 subunit beta; laminin-6 subunit beta; laminin-8 subunit beta; laminin-10 subunit beta; laminin-12 subunit beta; laminin B1; Laminin B1 chain; Laminin-1 subunit beta; Laminin-10 subunit beta; Laminin-12 subunit beta; Laminin-2 subunit beta; Laminin-6 subunit beta; Laminin-8 subunit beta]
products gene name :
[LAMb1]
other gene names :
[Lamb1; Lamb1; C77966; C80098; C81607; Lamb-1; Lamb1-1; D130003D08Rik; Lamb-1; Lamb1-1]
uniprot entry name :
LAMB1_MOUSE
form :
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300
concentration :
Original concentration: 200 ug/mL
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Positive Control, Immunogen, SDS-PAGE, WB. (May be suitable for use in other assays to be determined by the end user.)
image1 heading :
SDS-Page
other info1 :
Source: Prokaryotic expression. Residues: Gln1053~Lys1258. Tags: N-terminal His and GST Tag. Subcellular Location: Secreted, extracellular matrix. Traits: Freeze-dried powder. Predicted isoelectric point: 5.8. Predicted Molecular Mass: 52.3kDa. Accurate Molecular Mass: 52kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
ncbi pathways :
Alpha6-Beta4 Integrin Signaling Pathway (198373); Amoebiasis Pathway (167330); Amoebiasis Pathway (167191); Axon Guidance Pathway (926383); Degradation Of The Extracellular Matrix Pathway (927074); Developmental Biology Pathway (926382); ECM Proteoglycans Pathway (927073); ECM-receptor Interaction Pathway (83265); ECM-receptor Interaction Pathway (479); Extracellular Matrix Organization Pathway (927061)
uniprot summary :
LAMB1: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted. Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space; laminin-8 complex; laminin-2 complex; laminin-1 complex; perinuclear region of cytoplasm; laminin-10 complex; extracellular region; basement membrane; basal lamina. Molecular Function: integrin binding; protein binding; enzyme binding; extracellular matrix structural constituent; glycosphingolipid binding. Biological Process: odontogenesis; cell migration; learning and/or memory; neuronal-glial interaction involved in cerebral cortex radial glia guided migration; negative regulation of cell adhesion; cell adhesion; neurite development; embryo implantation; positive regulation of cell migration