product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Lymphocyte Activation Gene 3 (LAG3)
catalog :
MBS2009196
quantity :
0.01 mg
price :
175 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2009196
products type :
Recombinant Protein
products full name :
Recombinant Lymphocyte Activation Gene 3 (LAG3)
products short name :
Lymphocyte Activation Gene 3 (LAG3)
other names :
lymphocyte activation gene 3 protein; Lymphocyte activation gene 3 protein; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Protein FDC
products gene name :
LAG3
other gene names :
LAG3; LAG3; CD223; FDC; LAG-3
uniprot entry name :
LAG3_HUMAN
host :
E Coli
sequence length :
525
sequence :
The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- TYRDGFN VSIMYNLTVL GLEPPTPLTV YAGAGSRVGL PCRLPAGVGT RSFLTAKWTP PGGGPDLLVT GDNGDFTLRL EDVSQAQAGT YTCHIHLQEQ QLNATVTLAI ITVTPKSFGS PGSLGKLLCE VTPVSGQERF VWSSLDTPSQ RSFSGPWLEA QEAQLLSQPW QCQLYQGERL LGAAVYFTEL SSPGAQRSGR APGALPAGHL LLFLILGVLS LLLLVTGAFG FHLWRRQWRP RRFSALE
purity :
> 95%
form :
Supplied as lyophilized form in 20mM Tris, 500mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
storage stability :
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
tested application :
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
other info1 :
Organism: Homo sapiens (Human). Expression System: Prokaryotic expression. Residues: Thr244~Glu487 (Accession # P18627) with two N-terminal Tags, His-tag and T7-tag. Predicted isoelectric point: 8.8 . Predicted Molecular Mass: 30.2kDa
other info2 :
Endotoxin Level: <1.0EU per 1ug (determined by the LAL method). Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4. Residues: Thr244~Glu487 (Accession # P18627), with two N-terminal Tags, His-tag and T7-tag.
products description :
About the Marker: Effective Size Range: 10kDa to 70kDa. Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa. Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy. Ready-to-use: No need to heat, dilute or add reducing agents before use.
ncbi gi num :
167614500
ncbi acc num :
NP_002277.4
ncbi gb acc num :
NM_002286.5
uniprot acc num :
P18627
ncbi mol weight :
34kDa
ncbi summary :
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008]
uniprot summary :
LAG3: Involved in lymphocyte activation. Binds to HLA class-II antigens. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 12p13.32. Cellular Component: integral to membrane; external side of plasma membrane. Molecular Function: transmembrane receptor activity; antigen binding; MHC class II protein binding. Biological Process: cell surface receptor linked signal transduction; negative regulation of interleukin-2 biosynthetic process; positive regulation of natural killer cell mediated cytotoxicity; negative regulation of T cell activation
size1 :
0.01 mg
price1 :
175 USD
size2 :
0.05 mg
price2 :
370
size3 :
0.1 mg
price3 :
575
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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