Recombinant Oxytocin Receptor (OXTR) | MyBioSource MBS2009192 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Oxytocin Receptor (OXTR)

catalog :

MBS2009192

quantity :

0.01 mg

price :

135 USD

more info or order :

MyBioSource product webpage

image

image 1 :

image 2 :

product information

catalog number :

MBS2009192

products type :

Recombinant Protein

products full name :

Recombinant Oxytocin Receptor (OXTR)

products short name :

[Oxytocin Receptor (OXTR)]

other names :

[oxytocin receptor; Oxytocin receptor; oxytocin receptor; oxytocin receptor]

products gene name :

[OXTR]

other gene names :

[OXTR; OXTR; OT-R; OT-R]

uniprot entry name :

OXYR_HUMAN

host :

E Coli

reactivity :

Homo sapiens

sequence length :

389

sequence :

The target protein is fused with two N-terminal Tags, His-tag and GST-tag, its sequence is listed below. MRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTLEV LFQGPLGSEF- RTVKMTFII VLAFIVCWTP FFFVQMWSVW DANAPKEASA FIIVMLLASL NSCCNPWIYM LFTGHLFHEL VQRFLCCSAS YLKGRRLGET SASKKSNSSS FVLSHRS

purity :

> 95%

form :

20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300.

storage stability :

Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

tested application :

SDS-PAGE; WB; ELISA; IP; CoIP; ReporterAssays; Purification; Amine Reactive Labeling.(May be suitable for use in other assays to be determined by the end user.)

image1 heading :

Sequence Information

image2 heading :

SDS-Page

other info1 :

Tissue Specificity: Ovary. Subcellular Location: Cell membrane; Multi-pass membrane protein. Residues: Arg272~Ser377 with two N-terminal Tags, His-tag and GST-tag. Traits: Freeze-dried powder

other info2 :

Predicted isoelectric point: 5.5. Predicted Molecular Mass: 42.1kDa. Accurate Molecular Mass: 42kDa as determined by SDS-PAGE reducing conditions. Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

ncbi gi num :

32307152

ncbi acc num :

NP_000907.2

ncbi gb acc num :

NM_000916.3

uniprot acc num :

P30559

ncbi mol weight :

39.2kDa

ncbi pathways :

Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class A Rhodopsin-like Pathway (198886); Gastrin-CREB Signalling Pathway Via PKC And MAPK (645295); Myometrial Relaxation And Contraction Pathways (198759); Neuroactive Ligand-receptor Interaction Pathway (83053)

ncbi summary :

The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008]

uniprot summary :

OXTR: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral. Chromosomal Location of Human Ortholog: 3p25. Cellular Component: cell-cell adherens junction; microvillus; integral to plasma membrane; apical plasma membrane; plasma membrane. Molecular Function: oxytocin receptor activity; peptide hormone binding; peptide binding; vasopressin receptor activity. Biological Process: lactation; response to peptide hormone stimulus; response to anoxia; heart development; female pregnancy; positive regulation of synaptic transmission, glutamatergic; response to estradiol stimulus; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; muscle contraction; response to drug; maternal behavior; eating behavior; response to amphetamine; positive regulation of synaptic transmission, GABAergic; social behavior; response to cocaine; sleep; memory; cellular response to hormone stimulus; G-protein coupled receptor protein signaling pathway; positive regulation of synaptogenesis; telencephalon development; regulation of systemic arterial blood pressure by vasopressin; suckling behavior; gut development; response to cytokine stimulus; maternal process involved in parturition; positive regulation of vasoconstriction; sperm ejaculation; response to progesterone stimulus; positive regulation of blood pressure

size1 :

0.01 mg

price1 :

135 USD

size2 :

0.05 mg

price2 :

245

size3 :

0.1 mg

price3 :

365

size4 :

0.2 mg

price4 :

450

size5 :

0.5 mg

price5 :

870

size6 :

1 mg

price6 :

1280

more info or order :

MyBioSource product webpage