product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant FK506 Binding Protein 10 (FKBP10)
catalog :
MBS2009161
quantity :
0.01 mg
price :
165 USD
more info or order :
image
image 1 :
image 2 :
product information
catalog number :
MBS2009161
products type :
Recombinant Protein
products full name :
Recombinant FK506 Binding Protein 10 (FKBP10)
products short name :
[FK506 Binding Protein 10 (FKBP10)]
other names :
[peptidyl-prolyl cis-trans isomerase FKBP10; Peptidyl-prolyl cis-trans isomerase FKBP10; peptidyl-prolyl cis-trans isomerase FKBP10; FKBP-10; FKBP-65; rotamase; 65 kDa FKBP; PPIase FKBP10; immunophilin FKBP65; FK506-binding protein 10; 65 kDa FK506-binding protein; FK506 binding protein 10, 65 kDa; 65 kDa FK506-binding protein; 65 kDa FKBP; FKBP-65; FK506-binding protein 10; FKBP-10; Immunophilin FKBP65; Rotamase]
products gene name :
[FKBP10]
other gene names :
[FKBP10; FKBP10; OI6; OI11; FKBP65; PPIASE; hFKBP65; FKBP65; PPIase FKBP10; 65 kDa FKBP; FKBP-65; FKBP-10]
uniprot entry name :
FKB10_HUMAN
host :
E. coli
purity :
> 90%
form :
100mMNaHCO3, 500mMNaCl, pH8.3, containing 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
concentration :
Original Concentration: 200ug/mL
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Positive Control; Immunogen; SDS-PAGE; Western Blot (WB).
image1 heading :
Sequence Information
image2 heading :
SDS-Page
other info1 :
Organism Species: Homo sapiens (Human). Source: Prokaryotic expression. Residues: Val158~Asp440. Tags: N-terminal His Tag. Subcellular Location: Endoplasmic reticulum lumen
other info2 :
Traits: Freeze-dried powder. Predicted isoelectric point: 6.1. Usage: Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.
ncbi gi num :
192448443
ncbi acc num :
NP_068758.3
ncbi gb acc num :
NM_021939.3
uniprot acc num :
Q96AY3
ncbi mol weight :
Predicted Molecular Mass: 32.5kDa. Accurate Molecular Mass: 33kDa as determined by SDS-PAGE reducing conditions.
ncbi summary :
The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone. Alternatively spliced variants encoding different isoforms have been reported, but their biological validity has not been determined.[provided by RefSeq, Nov 2009]
uniprot summary :
FKBP10: PPIases accelerate the folding of proteins during protein synthesis. Defects in FKBP10 are the cause of osteogenesis imperfecta type 6 (OI6). OI6 is a moderate to severe, autosomal recessive form of osteogenesis imperfecta characterized by increased serum alkaline phosphatase levels and bone histology exhibiting a fish scale-like lamellar pattern. Osteogenesis imperfecta defines a group of connective tissue disorders characterized by bone fragility and low bone mass. Protein type: EC 5.2.1.8; Isomerase. Chromosomal Location of Human Ortholog: 17q21.2. Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum lumen. Molecular Function: peptidyl-prolyl cis-trans isomerase activity; FK506 binding; calcium ion binding. Biological Process: protein peptidyl-prolyl isomerization. Disease: Osteogenesis Imperfecta, Type Xi; Bruck Syndrome 1
size1 :
0.01 mg
price1 :
165 USD
size2 :
0.05 mg
price2 :
325
size3 :
0.1 mg
price3 :
505
size4 :
0.2 mg
price4 :
625
size5 :
0.5 mg
price5 :
1215
size6 :
1 mg
price6 :
1810
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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