product summary
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company name :
MyBioSource
product type :
antibody
product name :
Biotin-Linked Antibody to Podocin (PDCN)
catalog :
MBS2008292
quantity :
0.1 mg
price :
225 USD
clonality :
polyclonal
host :
rabbit
conjugate :
biotin
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2008292
products type :
Antibody
products full name :
Biotin-Linked Antibody to Podocin (PDCN)
products short name :
[Podocin (PDCN)]
other names :
[podocin; Podocin; podocin; nephrosis 2, idiopathic, steroid-resistant (podocin)]
products gene name :
[PDCN]
other gene names :
[NPHS2; NPHS2; PDCN; SRN1]
uniprot entry name :
PODO_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human
purity :
Antigen-specific Affinity Chromatography.
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
concentration :
200ug/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
app notes :
Western blotting: 0.5-2ug/ml. Immunocytochemistry in formalin fixed cells: 5-20ug/ml. Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml. Immunohistochemistry in paraffin section: 5-20ug/ml. Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml. Optimal working dilutions must be determined by end user.
other info1 :
Source: Antibody labeling. Label: Biotin. Traits: Liquid
other info2 :
Immunogen: Recombinant PDCN (Met222~Pro372) expressed in E.coli.
products categories :
Biotin Antibody
ncbi gi num :
7657615
ncbi acc num :
NP_055440.1
ncbi gb acc num :
NM_014625.2
uniprot acc num :
Q9NP85
ncbi pathways :
Nephrin/Neph1 Signaling In The Kidney Podocyte Pathway (138072)
ncbi summary :
This gene encodes a protein that plays a role in the regulation of glomerular permeability. Mutations in this gene cause steroid-resistant nephrotic syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
uniprot summary :
NPHS2: Plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton. Defects in NPHS2 are the cause of nephrotic syndrome type 2 (NPHS2). It is a renal disorder characterized clinically by childhood onset of proteinuria, hypoalbuminemia, hyperlipidemia, and edema. Kidney biopsies show non-specific histologic changes such as focal segmental glomerulosclerosis and diffuse mesangial proliferation. The disorder is resistant to steroid treatment and progresses to end-stage renal failure in the first or second decades. Some patients show later onset of the disorder. Belongs to the band 7/mec-2 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 1q25.2. Cellular Component: protein complex; endoplasmic reticulum; integral to plasma membrane; plasma membrane; intercellular junction; lipid raft. Molecular Function: protein binding. Biological Process: actin cytoskeleton reorganization; excretion. Disease: Nephrotic Syndrome, Type 2
size1 :
0.1 mg
price1 :
225 USD
size2 :
0.2 mg
price2 :
335
size3 :
1 mg
price3 :
795
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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