Biotin-Linked Antibody to Glutathione (GSH) | MyBioSource MBS2007760 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Biotin-Linked Antibody to Glutathione (GSH)

catalog :

MBS2007760

quantity :

0.1 mg

price :

220 USD

clonality :

polyclonal

host :

rabbit

conjugate :

biotin

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2007760

products type :

Antibody

products full name :

Biotin-Linked Antibody to Glutathione (GSH)

products short name :

[Glutathione (GSH)]

other names :

[glutathione S-transferase Mu 2 isoform 2; Glutathione S-transferase Mu 2; glutathione S-transferase Mu 2; GST, muscle; GST class-mu 2; glutathione S-transferase 4; glutathione S-transferase M1; glutathione S-aryltransferase M2; glutathione S-alkyltransferase M2; glutathione S-aralkyltransferase M2; S-(hydroxyalkyl)glutathione lyase M2; glutathione S-transferase M2 (muscle); glutathione S-transferase mu 2 (muscle); GST class-mu 2; GSTM2-2]

products gene name :

[GSH]

other gene names :

[GSTM2; GSTM2; GST4; GSTM; GTHMUS; GSTM2-2; GST4]

uniprot entry name :

GSTM2_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

sequence length :

191

specificity :

The antibody is a rabbit polyclonal antibody raised against GSH conjugated to biotin. It has been selected for its ability to recognize GSH in immunohistochemical staining andwestern blotting.

purity :

Antigen-specific Afinnity Chromatography.

form :

Supplied as solution form in 0.01M BBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

concentration :

0.23 mg/mL

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

IHC; ICC; IP.

app notes :

Immunohistochemistry: 5-20 Ug/mL. Immunocytochemistry: 5-20 Ug/mL. Optimal working dilutions must be determined by end user.

other info1 :

. Source: Antibody labeling. Label: Biotin. Traits: Liquid

other info2 :

Unconjugated Antibody: The unconjugated antibody version of this item is also available as catalog #MBS2005791

products categories :

Biotin Antibody

ncbi gi num :

215277000

ncbi acc num :

NP_001135840.1

ncbi gb acc num :

NM_001142368.1

uniprot acc num :

P28161

ncbi pathways :

Biological Oxidations Pathway (105698); Chemical Carcinogenesis Pathway (673221); Chemical Carcinogenesis Pathway (673237); Drug Metabolism - Cytochrome P450 Pathway (83032); Drug Metabolism - Cytochrome P450 Pathway (427); Glutathione Conjugation Pathway (105727); Glutathione Metabolism Pathway (82973); Glutathione Metabolism Pathway (198824); Glutathione Metabolism Pathway (343); Metabolism Pathway (477135)

ncbi summary :

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. [provided by RefSeq, Jul 2008]

uniprot summary :

GSTM2: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Mu family. Protein type: Transferase; EC 2.5.1.18; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 1p13.3. Cellular Component: sarcoplasmic reticulum; cytoplasm; cytosol. Molecular Function: enzyme binding; protein homodimerization activity; glutathione transferase activity; glutathione binding; receptor binding. Biological Process: regulation of skeletal muscle contraction via regulation of the release of sequestered calcium ion; glutathione metabolic process; nitrobenzene metabolic process; xenobiotic metabolic process; xenobiotic catabolic process

size1 :

0.1 mg

price1 :

220 USD

size2 :

0.2 mg

price2 :

325

size3 :

1 mg

price3 :

770

more info or order :

MyBioSource product webpage