product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Polyclonal Antibody to Urocortin 3 (UCN3)
catalog :
MBS2007025
quantity :
0.01 mg
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
image
image 1 :
Western Blot: Sample: Mouse Liver Tissue.
image 2 :
Western Blot: Sample: Recombinant UCN3, Mouse.
image 3 :
DAB staining on IHC-P; Samples: Mouse Intestine Tissue.
product information
catalog number :
MBS2007025
products type :
Antibody
products full name :
Polyclonal Antibody to Urocortin 3 (UCN3)
products short name :
[Urocortin 3 (UCN3)]
other names :
[urocortin-3 preproprotein; Urocortin-3; urocortin-3; urocortin 3; Urocortin III; Ucn III]
products gene name :
[UCN3]
other gene names :
[Ucn3; Ucn3; ucn III; Ucn III]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Mouse
specificity :
The antibody is a Rabbit polyclonal antibody raised against UCN3. It has been selected for its ability to recognize UCN3 in immunohistochemical staining and western blotting.
purity :
Antigen-specific Affinity Chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol
concentration :
200µg/mL
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP
app notes :
Western blotting: 0.5-2µg/mL. Immunohistochemistry: 5-20µg/mL. Immunocytochemistry: 5-20µg/mL. Optimal working dilutions must be determined by end user
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
image3 heading :
Immunohistochemistry (IHC)
image4 heading :
Immunohistochemistry (IHC)
image4 description :
DAB staining on IHC-P; Samples: Mouse Lung Tissue
image5 heading :
Immunohistochemistry (IHC)
image5 description :
DAB staining on IHC-P; Samples: Mouse Spleen Tissue
other info1 :
Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant UCN3 (His24~Lys149) expressed in E.coli.
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2070203
ncbi gi num :
21492632
ncbi acc num :
NP_112540.2
ncbi gb acc num :
NM_031250.5
uniprot acc num :
Q924A4
ncbi mol weight :
18,063 Da
ncbi pathways :
Class B/2 (Secretin Family Receptors) Pathway (1367080); GPCR Ligand Binding Pathway (1367054); Signal Transduction Pathway (1366876); Signaling By GPCR Pathway (1367053)
ncbi summary :
This gene encodes a member of the corticotropin-releasing hormone peptide family that participates in coordinating autonomic, endocrine, and behavioral responses to stress. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional hormone. The pancreatic islets isolated from mice lacking the encoded protein secrete less insulin in response to high glucose concentrations. Transgenic mice overexpressing the encoded protein exhibit a metabolically favorable phenotype resisting obesity and hyperglycemia on a high-fat diet. [provided by RefSeq, Sep 2016]
uniprot summary :
UCN3: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress. Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 13 13 A1. Cellular Component: axon; axon terminus; extracellular region; extracellular space; neuron projection. Molecular Function: corticotropin-releasing hormone receptor 2 binding; G-protein coupled receptor binding; hormone activity; neuropeptide hormone activity; protein binding. Biological Process: adenylate cyclase-activating G-protein coupled receptor signaling pathway; cellular response to nutrient levels; digestion; neuropeptide signaling pathway; positive regulation of insulin secretion; positive regulation of membrane potential; response to stress
size1 :
0.01 mg
price1 :
110 USD
size2 :
0.02 mg
price2 :
130
size3 :
0.05 mg
price3 :
185
size4 :
0.1 mg
price4 :
230
size5 :
0.2 mg
price5 :
345
size6 :
1 mg
price6 :
825
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!
browse more products
questions and comments