product summary
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company name :
MyBioSource
product type :
antibody
product name :
Polyclonal Antibody to Lymphocyte Activation Gene 3 (LAG3)
catalog :
MBS2006574
quantity :
0.01 mg
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2006574 image 1
Western Blot: Sample: Recombinant LAG3, Mouse.
product information
catalog number :
MBS2006574
products type :
Antibody
products full name :
Polyclonal Antibody to Lymphocyte Activation Gene 3 (LAG3)
products short name :
[Lymphocyte Activation Gene 3 (LAG3)]
other names :
[lymphocyte activation gene 3 protein; Lymphocyte activation gene 3 protein; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; CD_antigen: CD223]
products gene name :
[LAG3]
other gene names :
[Lag3; Lag3; Ly66; CD223; LAG-3; LAG-3]
clonality :
Polyclonal
host :
Rabbit
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
concentration :
1 mg/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP.
app notes :
Western blotting: 0.5-2 Ug/mL;1:500-2000 . Immunohistochemistry: 5-20 Ug/mL;1:50-200. Immunocytochemistry: 5-20 Ug/mL;1:50-200. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
other info1 :
Organism Species: Mus musculus (Mouse). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant LAG3 (Leu274~Gln504 (Accession # Q61790)) expressed in E.coli
ncbi gi num :
6678654
ncbi acc num :
NP_032505.1
ncbi gb acc num :
NM_008479.2
uniprot acc num :
Q61790
uniprot summary :
LAG3: a cell surface receptor involved in lymphocyte activation and neural function. LAG3 expressed on neurons is a receptor that binds extracellular Alpha-synuclein fibrils (PFF) with high affinity, leading to its endocytosis. LAG3 facilitates the neuron-to-neuron spread of PFF and its associated neural toxicity. Binds to HLA class-II antigens. Two isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 6 6 F2. Cellular Component: external side of plasma membrane; integral component of membrane; membrane. Molecular Function: MHC class II protein binding; transmembrane receptor activity. Biological Process: cell surface receptor signaling pathway; negative regulation of interleukin-2 biosynthetic process; negative regulation of T cell activation; positive regulation of natural killer cell mediated cytotoxicity
size1 :
0.01 mg
price1 :
110 USD
size2 :
0.02 mg
price2 :
125
size3 :
0.05 mg
price3 :
175
size4 :
0.1 mg
price4 :
225
size5 :
0.2 mg
price5 :
330
size6 :
1 mg
price6 :
785
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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