Polyclonal Antibody to Cathelicidin Antimicrobial Peptide (CAMP) | MyBioSource MBS2006075 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Cathelicidin Antimicrobial Peptide (CAMP)

catalog :

MBS2006075

quantity :

0.01 mg

price :

135 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay, immunohistochemistry - paraffin section

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2006075

products type :

Antibody

products full name :

Polyclonal Antibody to Cathelicidin Antimicrobial Peptide (CAMP)

products short name :

Cathelicidin Antimicrobial Peptide (CAMP)

other names :

cathelicidin antimicrobial peptide; Cathelicidin antimicrobial peptide; cathelicidin antimicrobial peptide; 18 kDa cationic antimicrobial protein; cathelicidin antimicrobial peptide; 18 kDa cationic antimicrobial protein; CAP-18; hCAP-18Cleaved into the following 2 chains:Antibacterial protein FALL-39; Alternative name(s):; FALL-39 peptide antibiotic

products gene name :

CAMP

other gene names :

CAMP; CAMP; LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39; CAP18; FALL39; CAP-18; hCAP-18

uniprot entry name :

CAMP_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Mouse

sequence length :

173

sequence :

The target protein is fused with two N-terminal Tags, His-tag and GST-tag and its sequence is listed below. MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTLEV LFQGPLGSEF-SYRDAVLRAV DDFNQQSLDT NLYRLLDLDP EPQGDEDPDT PKSVRFRVKE TVCGKAERQL PEQCAFKEQG VVKQCMGAVT LNPAADSFDI SCNEPGAQPF RFKKISRLAG LLRKGGEKIG EKLKKIGQKI KNFFQKLVPQ PEQ

specificity :

The antibody is a rabbit polyclonal antibody raised against CAMP. It has been selected for its ability to recognize CAMP in immunohistochemical staining andwestern blotting.

purity :

Affinity Chromatography

form :

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.

concentration :

200ug/ml

storage stability :

Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

tested application :

Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)

app notes :

Western blotting: 1:100-400. Immunocytochemistry in formalin fixed cells: 1:100-500. Immunohistochemistry in formalin fixed frozen section: 1:100-500. Immunohistochemistry in paraffin section: 1:50-200. Enzyme-linked Immunosorbent Assay: 1:100-200

other info1 :

Immunogen: Recombinant CAMP (Ser31~Gln173) expressed in E.coli.

other info2 :

Quality Control: Content: The quality control contains recombinant CRP (Phe17~Pro224) disposed in loading buffer. Usage: 10uL per well when 3,3'-Diaminobenzidine(DAB) as the substrate. 5uL per well when used in enhanced chemilumescent (ECL). Note: The quality control is specifically manufactured as the positive control.Not used for other purposes. Loading Buffer: 100mM Tris(pH8.8), 2% SDS, 200mM NaCl, 50% glycerol,BPB 0.01%, NaN3 0.02%. Accession No.: RPC419Mu01

ncbi gi num :

119585258

ncbi acc num :

EAW64854.1

uniprot acc num :

P49913

ncbi mol weight :

19,301 Da

ncbi pathways :

Disease Pathway (530764); Integrated Pancreatic Cancer Pathway (711360); Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway (645267); Phagosomal Maturation (early Endosomal Stage) Pathway (645268); SREBP Signalling Pathway (219802); Salivary Secretion Pathway (153376); Salivary Secretion Pathway (153352); Tuberculosis Pathway (213780); Tuberculosis Pathway (213743)

ncbi summary :

This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2014]

uniprot summary :

CAMP: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. Belongs to the cathelicidin family. Protein type: Secreted; Secreted, signal peptide; Cell cycle regulation; Vesicle. Chromosomal Location of Human Ortholog: 3p21.3. Cellular Component: extracellular space; specific granule; cell projection; cell wall; cytosol. Molecular Function: protein binding. Biological Process: interaction with host; defense response to Gram-positive bacterium; positive regulation of angiogenesis; innate immune response in mucosa; killing by host of symbiont cells; defense response to bacterium; positive regulation of cell proliferation; antibacterial humoral response; positive regulation of protein amino acid phosphorylation; defense response to Gram-negative bacterium

size1 :

0.01 mg

price1 :

135 USD

size2 :

0.05 mg

price2 :

245

size3 :

0.1 mg

price3 :

325

more info or order :

MyBioSource product webpage