Polyclonal Antibody to Tomoregulin 1 (TR1) | MyBioSource MBS2006055 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Tomoregulin 1 (TR1)

catalog :

MBS2006055

quantity :

0.01 mg

price :

115 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Recombinant TR1, Human.

image 2 :

DABstainingonIHC-P.Samples:HumanTissue)

product information

catalog number :

MBS2006055

products type :

Antibody

products full name :

Polyclonal Antibody to Tomoregulin 1 (TR1)

products short name :

[Tomoregulin 1 (TR1)]

other names :

[MSANTD3-TMEFF1 fusion protein; Tomoregulin-1; MSANTD3-TMEFF1 fusion protein; MSANTD3-TMEFF1 readthrough; H7365; Transmembrane protein with EGF-like and one follistatin-like domain]

products gene name :

[TR1]

other gene names :

[MSANTD3-TMEFF1; TMEFF1; C9orf3-TMEFF1; C9orf30-TMEFF1; C9orf2; TR-1]

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

specificity :

The antibody is a Rabbit polyclonal antibody raised against TR1. It has been selected for its ability to recognize TR1 in immunohistochemical staining and western blotting.

purity :

Antigen-specific Affinity Chromatography

form :

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

concentration :

200ug/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

WB; IHC; ICC; IP

app notes :

Western blotting: 0.5-2µg/mL. Immunocytochemistry in formalin fixed cells: 5-20µg/mL. Immunohistochemistry in formalin fixed frozen section: 5-20µg/mL. Immunohistochemistry in paraffin section: 5-20µg/mL. Optimal working dilutions must be determined by end user

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

other info1 :

Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant TR1 (Glu79~Ala333) expressed in E.coli

other info2 :

Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2083833

ncbi gi num :

311771742

ncbi acc num :

NP_001185741.1

ncbi gb acc num :

NM_001198812.1

uniprot acc num :

Q8IYR6

ncbi mol weight :

37,757 Da

ncbi summary :

This locus represents naturally occurring read-through transcription from the neighboring MSANTD3 (Myb/SANT-like DNA-binding domain containing 3) and TMEFF1 (transmembrane protein with EGF-like and two follistatin-like domains 1) genes. The read-through transcript encodes a fusion protein that shares sequence identity with the products of each individual gene. [provided by RefSeq, Aug 2013]

uniprot summary :

TMEFF1: a single-pass type I membrane protein. May inhibit NODAL and BMP signaling during neural patterning. A member of the Cancer-Testis Antigen (CTA) superfamily. CTAs may play roles in embryonal development and tumor transformation or aspects of tumor progression. CTAs were once thought to be silenced in most normal adult tissues, with limited expression in fetal, placental, testis, and ovarian cells. These proteins are now known to be aberrantly expressed in various cancers and many are capable of eliciting humoral and cellular immune responses. Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues. Expressed in a variety of cancers cell lines and in myeloma cells. Belongs to the tomoregulin family. Two isoforms of the human protein are produced by alternative splicing. Note: This description may include information from RefSeq and UniProtKB. Protein type: Cancer Testis Antigen (CTA); Membrane protein, integral. Chromosomal Location of Human Ortholog: 9q31.1. Cellular Component: integral component of membrane; plasma membrane. Biological Process: multicellular organism development

size1 :

0.01 mg

price1 :

115 USD

size2 :

0.02 mg

price2 :

135

size3 :

0.05 mg

price3 :

190

size4 :

0.1 mg

price4 :

245

size5 :

0.2 mg

price5 :

370

size6 :

1 mg

price6 :

875

more info or order :

MyBioSource product webpage