product summary
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company name :
MyBioSource
product type :
antibody
product name :
Polyclonal Antibody to Crystallin Beta B2 (CRYbB2)
catalog :
MBS2006023
quantity :
0.01 mg
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
image
image 1 :
MyBioSource MBS2006023 image 1
Western Blot: Sample: Mouse Eye Tissue.
image 2 :
MyBioSource MBS2006023 image 2
Western Blot: Sample: Recombinant CRYbB2, Mouse.
product information
catalog number :
MBS2006023
products type :
Antibody
products full name :
Polyclonal Antibody to Crystallin Beta B2 (CRYbB2)
products short name :
[Crystallin Beta B2 (CRYbB2)]
other names :
[beta-crystallin B2; Beta-crystallin B2; beta-crystallin B2; crystallin, beta B2; Beta-B2 crystallin; Beta-crystallin Bp]
products gene name :
[CRYbB2]
other gene names :
[Crybb2; Crybb2; Cryb-2]
clonality :
Polyclonal
host :
Rabbit
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
concentration :
0.51mg/ml
storage stability :
Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Western blotting (WB); Immunocytochemistry (ICC); Immunohistochemistry (IHC); Immunoprecipitation (IP)
app notes :
Western blotting: 0.5-2 ug/mL;1:250-1000. Immunohistochemistry: 5-20 ug/mL;1:25-100. Immunocytochemistry: 5-20 ug/mL;1:25-100. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
other info1 :
Organism Species: Mus musculus (Mouse). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant CRYbB2 (Pro17~Arg191)expressed in E.coli.
ncbi gi num :
6681035
ncbi acc num :
NP_031799.1
ncbi gb acc num :
NM_007773.4
uniprot acc num :
P62696
ncbi pathways :
Wnt Signaling Pathway NetPath (198351)
ncbi summary :
This gene is a member of the beta-crystallin family. Beta crystallins, along with alpha and gamma crystallins, are the major proteins found in the eye lens. These proteins maintain the refractive index of the lens whilst also maintaining its transparency. Since lens central fiber cells lose their nuclei during development, crystallins are made and then retained throughout life, making them extremely stable proteins. Beta and gamma crystallins are considered be a superfamily and have a similar domain architecture, including four Greek Key motifs. Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. The protein encoded by this gene may have Ca2+-binding activity and could be associated with potential functions in the hippocampus and in sperm. Targeted knockout of this gene in mouse induces age-related cataract. A chain-terminating mutation in a similar gene in human was found to cause type 2 cerulean cataracts. [provided by RefSeq, Feb 2015]
uniprot summary :
CRYBB2: a major structural protein of the eye lens. A member of the beta/gamma-crystallin family. Defects are the cause of congenital cerulean type 2 cataract, sutural cataract with punctate and cerulean opacities, and Coppock-like cataract. Chromosomal Location of Human Ortholog: 5 F 5 55.38 cM. Molecular Function: identical protein binding; protein homodimerization activity; structural constituent of eye lens. Biological Process: camera-type eye development; visual perception
size1 :
0.01 mg
price1 :
110 USD
size2 :
0.02 mg
price2 :
130
size3 :
0.05 mg
price3 :
185
size4 :
0.1 mg
price4 :
230
size5 :
0.2 mg
price5 :
345
size6 :
1 mg
price6 :
825
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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