Polyclonal Antibody to Cathepsin V (CTSV) | MyBioSource MBS2006015 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Cathepsin V (CTSV)

catalog :

MBS2006015

quantity :

0.01 mg

price :

90 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, enzyme immunoassay, immunohistochemistry - paraffin section

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Recombinant protein.

image 2 :

DAB staining on IHC-P; Samples: Human Rectum Cancer Tissue

image 3 :

DAB staining on IHC-P; Samples: Human Liver Tissue.

product information

catalog number :

MBS2006015

products type :

Antibody

products full name :

Polyclonal Antibody to Cathepsin V (CTSV)

products short name :

[Cathepsin V (CTSV)]

other names :

[cathepsin L2 preproprotein; Cathepsin L2; cathepsin L2; cathepsin V; Cathepsin U; Cathepsin V]

products gene name :

[CTSV]

other gene names :

[CTSV; CTSV; CTSU; CATL2; CTSL2; CATL2; CTSL2; CTSU]

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Homo sapiens (Human)

sequence length :

334

sequence :

Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSGS-GEYSQGK HGFTMAMNAF GDMTNEEFRQ MMGCFRNQKF RKGKVFREPL FLDLPKSVDW RKKGYVTPVK NQKQCGSCWA FSATGALEGQ MFRKTGKLVS LSEQNLVDCS RPQGNQGCNG GFMARAFQYV KENGGLDSEE SYPYVAVDEI CKYRPENSVA NDTGFTVVAP GKEKALMKAV ATVGPISVAM DAGHSSFQFY KSGIYFEPDC SSKNLDHGVL VVGYGFEGAN SNNSKYWLVK NSWGPEWGSN GYVKIAKDKN NHCGIATAAS YPNV

specificity :

The antibody is a rabbit polyclonal antibody raised against CTSV. It has been selected for its ability to recognize CTSV in immunohistochemical staining andwestern blotting.

purity :

Antigen-specific Affinity Chromatography.

form :

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.

concentration :

200ug/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4oC for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB), IP, IF, FCM.

app notes :

Western blotting: 0.5-2ug/ml. Immunocytochemistry in formalin fixed cells: 5-20ug/ml. Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml. Immunohistochemistry in paraffin section: 5-20ug/ml. Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml. Optimal working dilutions must be determined by end user.

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

image3 heading :

Immunohistochemistry (IHC)

image4 heading :

Immunohistochemistry (IHC)

image4 description :

DAB staining on IHC-P; Samples: Human Kidney Tissue.

image5 heading :

Immunohistochemistry (IHC)

image5 description :

DAB staining on IHC-P; Samples: Human Prostate Gland Tissue.

other info1 :

Source: Polyclonal antibody preparation. Immunogen: Recombinant Cathepsin V (CTSV)

other info2 :

Traits: Liquid. Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2069226

ncbi gi num :

320118898

ncbi acc num :

NP_001188504.1

ncbi gb acc num :

NM_001201575.1

uniprot acc num :

O60911

ncbi mol weight :

37,329 Da

ncbi pathways :

Activation Of Matrix Metalloproteinases Pathway (576264); Adaptive Immune System Pathway (366160); Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway (730306); Collagen Formation Pathway (645288); Degradation Of The Extracellular Matrix Pathway (576263); Endochondral Ossification Pathway (198812); Extracellular Matrix Organization Pathway (576262); Immune System Pathway (106386); Lysosome Pathway (99052); Lysosome Pathway (96865)

ncbi summary :

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2011]

uniprot summary :

CTSL2: Cysteine protease. May have an important role in corneal physiology. Belongs to the peptidase C1 family. Protein type: EC 3.4.22.15; Protease; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 9q22.33. Cellular Component: apical part of cell; external side of plasma membrane; extracellular region; extracellular space; lysosomal lumen; lysosome; microvillus; neuron projection; perikaryon; secretory granule. Molecular Function: aminopeptidase activity; cysteine-type endopeptidase activity; cysteine-type peptidase activity; kininogen binding; peptide binding; protein binding; protein complex binding; serine-type endopeptidase activity. Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; autophagic cell death; cellular response to starvation; decidualization; extracellular matrix disassembly; multicellular organismal aging; nerve development; proteolysis involved in cellular protein catabolic process; regulation of keratinocyte differentiation; response to glucocorticoid stimulus; response to glucose stimulus; Sertoli cell differentiation; spermatogenesis

size1 :

0.01 mg

price1 :

90 USD

size2 :

0.02 mg

price2 :

105

size3 :

0.05 mg

price3 :

135

size4 :

0.1 mg

price4 :

170

size5 :

0.2 mg

price5 :

235

size6 :

1 mg

price6 :

540

more info or order :

MyBioSource product webpage