antibody

Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)

MBS2005722

0.01 mg

105 USD

polyclonal

rabbit

nonconjugated

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

Antibody

Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)

[Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)]

[CD70 antigen isoform 1; CD70 antigen; CD70 antigen; CD70 molecule; CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD_antigen: CD70]

[TNFSF7]

[CD70; CD70; CD27L; CD27-L; CD27LG; TNFSF7; TNLG8A; CD27L; CD27LG; TNFSF7; CD27-L]

Polyclonal

Rabbit

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

0.5mg/ml

Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

WB; IHC; ICC; IP.

Western blotting: 0.5-2ug/mL;1:250-1000. Immunohistochemistry: 5-20ug/mL;1:25-100. Immunocytochemistry: 5-20ug/mL;1:25-100. Optimal working dilutions must be determined by end user.

Western Blot (WB)

Immunohistochemistry (IHC)

Organism Species: Mus musculus (Mouse)). Source: Polyclonal antibody preparation. Traits: Liquid

Immunogen: Recombinant TNFSF7 (Leu64~Trp192 (Accession # O55237)) expressed in E.coli

4507605

NP_001243.1

NM_001252.4

O55237

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]

CD70: Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. Belongs to the tumor necrosis factor family. Protein type: Cytokine; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19p13.3. Cellular Component: integral component of plasma membrane; plasma membrane. Molecular Function: cytokine activity; protease binding; protein binding; receptor binding; tumor necrosis factor receptor binding. Biological Process: cell proliferation; cell-cell signaling; immune response; signal transduction; tumor necrosis factor-mediated signaling pathway

0.01 mg

105 USD

0.02 mg

125

0.05 mg

170

0.1 mg

220

0.2 mg

320

1 mg

760