catalog number :
MBS2005646
products full name :
Polyclonal Antibody to Glutathione S Transferase Alpha 4 (GSTa4)
products short name :
[Glutathione S Transferase Alpha 4 (GSTa4)]
other names :
[glutathione S-transferase A4; Glutathione S-transferase A4; glutathione S-transferase A4; glutathione S-transferase, alpha 4; GST A4-4; GSTA4-4; GST class-alpha member 4; Glutathione S-transferase 5.7; GST 5.7]
products gene name :
[GSTa4]
other gene names :
[Gsta4; Gsta4; GST5.7; mGsta4; Gsta; GSTA4-4; GST 5.7]
specificity :
The antibody is a Rabbit polyclonal antibody raised against GSTa4. It has been selected for its ability to recognize GSTa4 in immunohistochemical staining and western blotting.
purity :
Antigen-specific Affinity Chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
storage stability :
Storage : Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP
app notes :
Western blotting: 0.5-2µg/mL. Immunohistochemistry: 5-20µg/mL. Immunocytochemistry: 5-20µg/mL. Optimal working dilutions must be determined by end user
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant GSTa4 (Met1~Phe222) expressed in E.coli
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2045652
ncbi acc num :
NP_034487.2
ncbi gb acc num :
NM_010357.3
ncbi mol weight :
25,564 Da
ncbi pathways :
Amino Acid Metabolism Pathway (198416); Chemical Carcinogenesis Pathway (673229); Chemical Carcinogenesis Pathway (673237); Drug Metabolism - Cytochrome P450 Pathway (83229); Drug Metabolism - Cytochrome P450 Pathway (427); Glutathione Metabolism Pathway (83172); Glutathione Metabolism Pathway (343); Metabolism Of Xenobiotics By Cytochrome P450 Pathway (83228); Metabolism Of Xenobiotics By Cytochrome P450 Pathway (425); Metapathway Biotransformation (198377)
uniprot summary :
GSTA4: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This isozyme has a high catalytic efficiency with 4-hydroxyalkenals such as 4- hydroxynonenal (4-HNE). Belongs to the GST superfamily. Alpha family. Protein type: EC 2.5.1.18; Other Amino Acids Metabolism - glutathione; Transferase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450. Chromosomal Location of Human Ortholog: 9 9 E1. Cellular Component: cytoplasm; mitochondrion. Molecular Function: drug binding; glutathione binding; glutathione transferase activity; transferase activity. Biological Process: metabolic process