Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1) | MyBioSource MBS2005476 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1)

catalog :

MBS2005476

quantity :

0.01 mg

price :

110 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Recombinant protein.

image 2 :

DABstainingonIHC-P.Samples:RatTissue)

product information

catalog number :

MBS2005476

products type :

Antibody

products full name :

Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1)

products short name :

[Platelet/Endothelial Cell Adhesion Molecule (PECAM1)]

other names :

[platelet endothelial cell adhesion molecule; Platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule; platelet and endothelial cell adhesion molecule 1; CD_antigen: CD31]

products gene name :

[PECAM1]

other gene names :

[Pecam1; Pecam1; CD31; Pecam; Pecam; PECAM-1]

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Rat

specificity :

The antibody is a Rabbit polyclonal antibody raised against PECAM1. It has been selected for its ability to recognize PECAM1 in immunohistochemical staining and western blotting.

purity :

Antigen-specific Affinity Chromatography

form :

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol

concentration :

200ug/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

WB; IHC; ICC; IP

app notes :

Western blotting: 0.5-5µg/mL. Immunocytochemistry in formalin fixed cells: 5-20µg/mL. Immunohistochemistry in formalin fixed frozen section: 5-20µg/mL. Immunohistochemistry in paraffin section: 5-20µg/mL. Optimal working dilutions must be determined by end user

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

other info1 :

Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant PECAM1 (Arg459~Glu624) expressed in E.coli.

other info2 :

Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2041390

ncbi gi num :

75832033

ncbi acc num :

NP_113779.1

ncbi gb acc num :

NM_031591.1

uniprot acc num :

Q3SWT0

ncbi mol weight :

76,189 Da

ncbi pathways :

Cell Adhesion Molecules (CAMs) Pathway (83461); Cell Adhesion Molecules (CAMs) Pathway (480); Leukocyte Transendothelial Migration Pathway (83475); Leukocyte Transendothelial Migration Pathway (494); Malaria Pathway (152662); Malaria Pathway (152657)

ncbi summary :

cell adhesion molecule, also intracellular signaling molecule; may mediate leukocyte adhesion and migration, angiogenesis, and thrombosis [RGD, Feb 2006]

uniprot summary :

PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues. Protein type: Cell adhesion; Cell development/differentiation; Membrane protein, integral; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 10q32.1. Cellular Component: cell junction; cell surface; external side of plasma membrane; extracellular space; integral component of membrane; membrane; membrane raft; plasma membrane; ruffle; smooth muscle contractile fiber. Molecular Function: protein phosphatase binding. Biological Process: angiogenesis; cell adhesion; diapedesis; endothelial cell migration; endothelial cell morphogenesis; negative regulation of actin filament polymerization; negative regulation of peptidyl-tyrosine phosphorylation; phagocytosis; positive regulation of cellular extravasation; positive regulation of leukocyte migration; positive regulation of tyrosine phosphorylation of STAT protein; regulation of cell migration; Rho protein signal transduction; wound healing

size1 :

0.01 mg

price1 :

110 USD

size2 :

0.02 mg

price2 :

125

size3 :

0.05 mg

price3 :

175

size4 :

0.1 mg

price4 :

225

size5 :

0.2 mg

price5 :

330

size6 :

1 mg

price6 :

785

more info or order :

MyBioSource product webpage