catalog number :
MBS2005235
products full name :
Polyclonal Antibody to Hemopexin (HPX)
products short name :
[Hemopexin (HPX)]
other names :
[hemopexin; Hemopexin; hemopexin; hemopexin]
products gene name :
[HPX]
other gene names :
[Hpx; Hpx; Hpxn]
specificity :
The antibody is a rabbit polyclonal antibody raised against HPX. It has been selected for its ability to recognize HPX in immunohistochemical staining andwestern blotting.
purity :
Antigen-specific Affinity Chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol
storage stability :
Storage : Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM
app notes :
Western blotting: 0.5-2ug/ml. Immunocytochemistry in formalin fixed cells: 5-20ug/ml. Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml. Immunohistochemistry in paraffin section: 5-20ug/ml. Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant HPX (Glu31~Thr242) expressed in E.coli.
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2061588
ncbi acc num :
NP_445770.1
ncbi gb acc num :
NM_053318.1
ncbi mol weight :
51,351 Da
ncbi pathways :
Binding And Uptake Of Ligands By Scavenger Receptors Pathway (1376621); Scavenging Of Heme From Plasma Pathway (1376622); Vesicle-mediated Transport Pathway (1376592)
ncbi summary :
a heme binding globulin protein [RGD, Feb 2006]
uniprot summary :
HPX: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. Belongs to the hemopexin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1q32. Cellular Component: cell; extracellular space. Molecular Function: heme transporter activity; metal ion binding. Biological Process: cellular iron ion homeostasis; heme metabolic process; heme transport; hemoglobin metabolic process; positive regulation of humoral immune response mediated by circulating immunoglobulin; positive regulation of immunoglobulin production; positive regulation of tyrosine phosphorylation of STAT protein; regulation of protein metabolic process