product summary
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company name :
MyBioSource
product type :
antibody
product name :
Polyclonal Antibody to Sclerostin Domain Containing Protein 1 (SOSTDC1)
catalog :
MBS2005228
quantity :
0.01 mg
price :
135 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2005228
products type :
Antibody
products full name :
Polyclonal Antibody to Sclerostin Domain Containing Protein 1 (SOSTDC1)
products short name :
Sclerostin Domain Containing Protein 1 (SOSTDC1)
other names :
sclerostin domain-containing protein 1; Sclerostin domain-containing protein 1; sclerostin domain-containing protein 1; ectodermal BMP inhibitor; cystine-knot containing secreted protein; uterine sensitization-associated protein-1; sclerostin domain containing 1; Ectodermal BMP inhibitor; Ectodin; Uterine sensitization-associated gene 1 protein
products gene name :
SOSTDC1
other gene names :
SOSTDC1; SOSTDC1; USAG1; CDA019; ECTODIN; USAG1; Ectodin; USAG-1
uniprot entry name :
SOSD1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Mouse
sequence length :
206
sequence :
The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- FKNDATE ILYSHVVKPV PAHPSSNSTL NQARNGGRHF SSTGLDRNSR VQVGCRELRS TKYISDGQCT SISPLKELVC AGECLPLPVL PNWIGGGYGT KYWSRRSSQE WRCVNDKTRT QRIQLQCQDG STRTYKITVV TACKCKRYTR QHNESSHNFE SVSPAKPAQH HRERKRASKS SKHSLS
specificity :
The antibody is a rabbit polyclonal antibody raised against SOSTDC1. It has been selected for its ability to recognize SOSTDC1 in immunohistochemical staining and western blotting.
purity :
Affinity Chromatography
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
concentration :
200ug/ml
storage stability :
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
tested application :
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
app notes :
Western blotting: 1:50-400. Immunocytochemistry in formalin fixed cells: 1:50-500. Immunohistochemistry in formalin fixed frozen section: 1:50-500. Immunohistochemistry in paraffin section: 1:10-100. Enzyme-linked Immunosorbent Assay: 1:100-200. Optimal working dilutions must be determined by end user.
ncbi gi num :
23943785
ncbi acc num :
NP_056279.1
ncbi gb acc num :
NM_015464.2
uniprot acc num :
Q6X4U4
ncbi mol weight :
23,307 Da
ncbi pathways :
BMP Receptor Signaling Pathway (137948)
ncbi summary :
This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death. [provided by RefSeq, Jul 2008]
uniprot summary :
SOSTDC1: May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling. Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. Belongs to the sclerostin family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 7p21.1. Cellular Component: extracellular space. Biological Process: hair follicle morphogenesis; Wnt receptor signaling pathway; pattern specification process; odontogenesis of dentine-containing teeth; negative regulation of cell fate commitment; negative regulation of BMP signaling pathway
size1 :
0.01 mg
price1 :
135 USD
size2 :
0.05 mg
price2 :
245
size3 :
0.1 mg
price3 :
325
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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