product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Polyclonal Antibody to Alpha-2-Macroglobulin (a2M)
catalog :
MBS2004831
quantity :
0.01 mg
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2004831 image 1
Western Blot: Sample: . Lane 1: Mouse Heart Tissue. Lane 2: Mouse Liver Tissue. Lane 3: Mouse Brain Tissue.
image 2 :
MyBioSource MBS2004831 image 2
Western Blot: Sample: Recombinant a2M, Mouse.
image 3 :
MyBioSource MBS2004831 image 3
DAB staining on IHC-P; Samples: Mouse Testis Tissue.
product information
catalog number :
MBS2004831
products type :
Antibody
products full name :
Polyclonal Antibody to Alpha-2-Macroglobulin (a2M)
products short name :
[Alpha-2-Macroglobulin (a2M)]
other names :
[Pregnancy zone protein; Pregnancy zone protein; Alpha-2-macroglobulin; Alpha-2-M]
products gene name :
[a2M]
other gene names :
[Pzp; A2m; Alpha-2-M]
clonality :
Polyclonal
host :
Rabbit
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
concentration :
0.43 mg/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP).
app notes :
Western blotting: 0.5-2 ug/mL. Immunohistochemistry: 5-20 ug/mL. Immunocytochemistry: 5-20 ug/mL. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Organism Species: Mus musculus (Mouse). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant a2M (Trp1053~Ala1214) expressed in E.coli
ncbi gi num :
338817897
ncbi acc num :
Q61838.3
uniprot acc num :
Q61838
uniprot summary :
PZP: Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase. Belongs to the protease inhibitor I39 (alpha-2- macroglobulin) family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 6 F3 6 63.02 cM. Cellular Component: extracellular region; extracellular space. Molecular Function: brain-derived neurotrophic factor binding; endopeptidase inhibitor activity; nerve growth factor binding; peptidase inhibitor activity; protein complex binding; serine-type endopeptidase inhibitor activity. Biological Process: embryo implantation; negative regulation of peptidase activity
size1 :
0.01 mg
price1 :
110 USD
size2 :
0.02 mg
price2 :
125
size3 :
0.05 mg
price3 :
175
size4 :
0.1 mg
price4 :
225
size5 :
0.2 mg
price5 :
330
size6 :
1 mg
price6 :
780
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!