catalog number :
MBS2004827
products full name :
Polyclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3)
products short name :
[Monocyte Chemotactic Protein 3 (MCP3)]
other names :
[C-C motif chemokine 7; C-C motif chemokine 7; C-C motif chemokine 7; chemokine (C-C motif) ligand 7; Intercrine/chemokine MARC; Monocyte chemoattractant protein 3; Monocyte chemotactic protein 3; MCP-3; Protein FIC; Small-inducible cytokine A7]
products gene name :
[MCP3]
other gene names :
[Ccl7; Ccl7; fic; marc; mcp3; MCP-3; Scya7; Fic; Mcp3; Scya7; MCP-3]
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
concentration :
0.73 mg/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the
expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP.
app notes :
Western blotting: 0.5-2 Ug/mL;1:100-500. Immunohistochemistry: 5-20 Ug/mL;1:10-50. Immunocytochemistry: 5-20 Ug/mL;1:10-50.
Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
image4 heading :
Immunohistochemistry (IHC)
image4 description :
DAB staining on IHC-P; Samples: Mouse Testis Tissue.
other info1 :
Organism Species: Mus musculus (Mouse). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant MCP3 (Pro28~Pro97 (Accession # Q03366)) expressed in E.coli
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2037485
ncbi acc num :
NP_038682.1
ncbi gb acc num :
NM_013654.3
ncbi pathways :
Chemokine Receptors Bind Chemokines Pathway (1110501); Chemokine Signaling Pathway (99271); Chemokine Signaling Pathway (672435); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (1110499); Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1111486); Disease Pathway (1111319); GPCR Ligand Binding Pathway (1110498)
uniprot summary :
CCL7: Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3. Belongs to the intercrine beta (chemokine CC) family. Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 11 C 11 49.83 cM. Cellular Component: extracellular region; extracellular space. Molecular Function: CCR2 chemokine receptor binding; chemokine activity; cytokine activity; heparin binding. Biological Process: chemotaxis; G-protein coupled receptor signaling pathway; immune response; inflammatory response; lymphocyte chemotaxis; monocyte chemotaxis; neutrophil chemotaxis; positive regulation of GTPase activity