catalog number :
MBS2004478
products full name :
Polyclonal Antibody to Interleukin 17 (IL17)
products short name :
Interleukin 17 (IL17)
other names :
interleukin-17
products gene name :
IL17
sequence :
The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSGSEF-ISAHGK VIRPGLEPES LFKKADAGCL TQKDGKFPQT VRVNISISNM NQDTKVTLDI SKRSLAPWDY RIDEDHNRFP RLVADAQCRH SRCVNSAGQL DHSVNSVPIK QEILVLRREP KGCQHSYRLE KKMITVGCTC VTPLIQHQ
specificity :
The antibody is a rabbit polyclonal antibody raised against IL17. It has been selected for its ability to recognize IL17 in immunohistochemical staining and western blotting.
purity :
Antigen-specific Affinity Chromatography.
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store a t 4 degree C for frequent use. Aliquot and store a t -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB),IP, IF, FCM.
app notes :
Western blotting: 0.5-2ug/ml. Immunocytochemistry in formalin fixed cells: 5-20ug/ml. Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml. Immunohistochemistry in paraffin section: 5-20ug/ml. Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml. Optimal working dilutions must be determined by end user.
other info1 :
Source: Polyclonal antibody preparation. Immunogen: -Interleukin 17 (IL17)
ncbi acc num :
AAV41220.1
ncbi summary :
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]