Polyclonal Antibody to Aquaporin 4 (AQP4) | MyBioSource MBS2004472 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Aquaporin 4 (AQP4)

catalog :

MBS2004472

quantity :

0.01 mg

price :

130 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay, immunohistochemistry - paraffin section

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2004472

products type :

Antibody

products full name :

Polyclonal Antibody to Aquaporin 4 (AQP4)

products short name :

Aquaporin 4 (AQP4)

other names :

Aquaporin 4; Aquaporin-4; aquaporin-4; WCH4; aquaporin type4; aquaporin 4 isoform delta4; mercurial-insensitive water channel; aquaporin 4; Mercurial-insensitive water channel; MIWC; WCH4

products gene name :

AQP4

other gene names :

AQP4; AQP4; MIWC; HMIWC2; AQP-4; MIWC

uniprot entry name :

AQP4_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Mouse

sequence length :

323

sequence :

The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSGSEF-SCDS KRTDVTGSIA LAIGFSVAIG HLFAINYTGA SMNPARSFGP AVIMGNWANH WIYWVGPIMG AVLAGALYEY VFCPDVELKR RLKEAFSKAA QQTKGSYMEV EDNRSQVETE DLILKPGVVH VIDI

specificity :

The antibody is a rabbit polyclonal antibody raised against AQP4. It has been selected for its ability to recognize AQP4 in immunohistochemical staining andwestern blotting.

purity :

Affinity Chromatography

form :

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.

concentration :

200ug/ml

storage stability :

Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

tested application :

Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)

app notes :

Western blotting: 1:100-400. Immunocytochemistry in formalin fixed cells: 1:100-500. Immunohistochemistry in formalin fixed frozen section: 1:100-500. Immunohistochemistry in paraffin section: 1:50-200. Enzyme-linked Immunosorbent Assay: 1:100-200

other info1 :

UOM: 100ug

other info2 :

Quality Control: Content: The quality control contains recombinant AQP4 (Ser177~lle304) disposed in loading buffer. 5uL per well when used in enhanced chemilumescent (ECL). Note: The quality control is specifically manufactured as the positive control.Not used for other purposes. Loading Buffer: 100mM Tris(pH8.8), 2% SDS, 200mM NaCl, 50% glycerol,BPB 0.01%, NaN3 0.02%.

ncbi gi num :

18490380

ncbi acc num :

AAH22286.1

uniprot acc num :

P55087

ncbi mol weight :

34,830 Da

ncbi pathways :

Aquaporin-mediated Transport Pathway (187187); Bile Secretion Pathway (193146); Bile Secretion Pathway (193095); Passive Transport By Aquaporins Pathway (187188); Regulation Of Water Balance By Renal Aquaporins Pathway (187189); SIDS Susceptibility Pathways (198901); Spinal Cord Injury Pathway (739007); Transmembrane Transport Of Small Molecules Pathway (106572); Vasopressin-regulated Water Reabsorption Pathway (143700); Vasopressin-regulated Water Reabsorption Pathway (143631)

ncbi summary :

This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

AQP4: a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The predominant aquaporin found in brain. Two alternatively spliced transcript variants have been described. Protein type: Transporter; Transporter, aquaporin family; Membrane protein, multi-pass; Channel, misc.; Membrane protein, integral. Chromosomal Location of Human Ortholog: 18q11.2-q12.1. Cellular Component: protein complex; basolateral plasma membrane; integral to plasma membrane; T-tubule; cytoplasm; plasma membrane; intercellular junction; external side of plasma membrane. Molecular Function: water transporter activity; water channel activity; porin activity; glycerol channel activity. Biological Process: glycerol transport; cellular water homeostasis; water transport; carbon dioxide transport; response to glucocorticoid stimulus; female pregnancy; response to radiation; sensory perception of sound; hyperosmotic salinity response; transport; renal water homeostasis; multicellular organismal water homeostasis; transmembrane transport; protein homooligomerization

size1 :

0.01 mg

price1 :

130 USD

size2 :

0.05 mg

price2 :

225

size3 :

0.1 mg

price3 :

290

more info or order :

MyBioSource product webpage