catalog number :
MBS2004396
products full name :
Polyclonal Antibody to Bone Marrow Stromal Cell Antigen 1 (BST1)
products short name :
[Bone Marrow Stromal Cell Antigen 1 (BST1)]
other names :
[ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; bone marrow stromal cell antigen 1; ADP-ribosyl cyclase 2; Antigen BP3; BP-3 alloantigen; Bone marrow stromal antigen 1; BST-1; Cyclic ADP-ribose hydrolase 2; cADPr hydrolase 2; Leukocyte antigen 65; Ly-65; CD_antigen: CD157]
products gene name :
[BST1]
other gene names :
[Bst1; Bst1; Bp3; BP-3; Ly65; Bsta1; CD157; 114/A10; A530073F09; Bp-3; Bp3; Ly65; BST-1; cADPr hydrolase 2; Ly-65]
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
concentration :
0.38mg/ml
storage stability :
Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blot (WB), Immunoprecipitation (IP)
app notes :
Western blotting: 0.5-2 ug/mL;1:190-760. Immunohistochemistry: 5-20 ug/mL;1:19-76. Immunocytochemistry: 5-20 ug/mL;1:19-76. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Organism Species: Mus musculus (Mouse). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant BST1 (Arg28~Met282 (Accession #Q64277)) expressed in E.coli
ncbi acc num :
NP_033893.2
ncbi gb acc num :
NM_009763.3
ncbi pathways :
Metabolic Pathways (132962); Nicotinate And Nicotinamide Metabolism Pathway (83212); Nicotinate And Nicotinamide Metabolism Pathway (400); Pancreatic Secretion Pathway (169307); Pancreatic Secretion Pathway (169295); Salivary Secretion Pathway (153377); Salivary Secretion Pathway (153352); Pyridine Nucleotide Cycling Pathway (142870)
uniprot summary :
BST1: Synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. Belongs to the ADP-ribosyl cyclase family. Protein type: Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; EC 3.2.2.6; Hydrolase; Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 5 B3 5 23.84 cM. Cellular Component: extracellular exosome; extrinsic component of membrane; integrin complex; membrane; plasma membrane; uropod. Molecular Function: ADP-ribosyl cyclase activity; cyclic ADP-ribose hydrolase; hydrolase activity; NAD(P)+ nucleosidase activity; NAD+ nucleosidase activity; NAD+ nucleotidase, cyclic ADP-ribose generating; phosphorus-oxygen lyase activity; transferase activity. Biological Process: positive regulation of B cell proliferation; positive regulation of cell proliferation; regulation of actin cytoskeleton organization; regulation of calcium-mediated signaling; regulation of cell-matrix adhesion; regulation of inflammatory response; regulation of neutrophil chemotaxis; regulation of peptidyl-tyrosine phosphorylation