Polyclonal Antibody to Procollagen C Proteinase Enhancer 1 (PCPE1) | MyBioSource MBS2004251 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Procollagen C Proteinase Enhancer 1 (PCPE1)

catalog :

MBS2004251

quantity :

0.01 mg

price :

135 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

MyBioSource product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:100; fig s4	Papke C, Tsunezumi J, Ringuette L, Nagaoka H, Terajima M, Yamashiro Y, et al. Loss of fibulin-4 disrupts collagen synthesis and maturation: implications for pathology resulting from EFEMP2 mutations. Hum Mol Genet. 2015;24:5867-79 pubmed publisher

product information

catalog number :

MBS2004251

products type :

Antibody

products full name :

Polyclonal Antibody to Procollagen C Proteinase Enhancer 1 (PCPE1)

products short name :

Procollagen C Proteinase Enhancer 1 (PCPE1)

other names :

procollagen C-endopeptidase enhancer 1; Procollagen C-endopeptidase enhancer 1; procollagen C-endopeptidase enhancer 1; procollagen C-proteinase enhancer 1; procollagen COOH-terminal proteinase enhancer 1; type 1 procollagen C-proteinase enhancer protein; type I procollagen COOH-terminal proteinase enhancer; procollagen, type 1, COOH-terminal proteinase enhancer; procollagen C-endopeptidase enhancer; Procollagen COOH-terminal proteinase enhancer 1; PCPE-1; Procollagen C-proteinase enhancer 1; Type 1 procollagen C-proteinase enhancer protein; Type I procollagen COOH-terminal proteinase enhancer

products gene name :

PCPE1

other gene names :

PCOLCE; PCOLCE; PCPE; PCPE1; PCPE-1; PCPE1; PCPE-1

uniprot entry name :

PCOC1_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Mouse

sequence length :

449

sequence :

The target protein is fused with a His-tag and its sequence is listed below. MGHHHHHHSGSEF-CGGDV TGESGYVASE GFPNLYPPNK KCIWTITVPE GQTVSLSFRV FDMELHPSCR YDALEVFAGS GTSGQRLGRF CGTFRPAPVV APGNQVTLRM TTDEGTGGRG FLLWYSGRAT SGTEHQFCGG RMEKAQGTLT TPNWPESDYP PGISCSWHII APSNQVIMLT FGKFDVEPDT YCRYDSVSVF NGAVSDDSKR LGKFCGDKAP SPISSEGNEL LVQFVSDLSV TADGFSASYR TLPRDAVEKE SALSPGEDVQ RGPQSRSDPK TGTGPKVKPP TKPKSQPAET PEASPATQAT PVAPAAPSIT CPKQYKRSGT LQSNFCSSSL VVTGTVKTMV RGPGEGLTVT VSLLGVYKTG GLDLPSPPSG TSLKLYVPCR QMPPMKKGAS YLLMGQVEEN RGPILPPESF VVLYRSNQDQ ILNNLSKRKC PSQPRTAA

specificity :

The antibody is a rabbit polyclonal antibody raised against PCPE1. It has been selected for its ability to recognize PCPE1 in immunohistochemical staining and western blotting.

purity :

Affinity Chromatography

form :

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.

concentration :

200ug/ml

storage stability :

Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

tested application :

Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)

app notes :

Western blotting: 1:50-400. Immunocytochemistry in formalin fixed cells: 1:50-500. Immunohistochemistry in formalin fixed frozen section: 1:50-500. Immunohistochemistry in paraffin section: 1:10-100. Enzyme-linked Immunosorbent Assay: 1:100-200

ncbi gi num :

157653329

ncbi acc num :

NP_002584.2

ncbi gb acc num :

NM_002593.3

uniprot acc num :

Q15113

ncbi mol weight :

47,972 Da

ncbi pathways :

Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway (730306); Collagen Biosynthesis And Modifying Enzymes Pathway (645289); Collagen Formation Pathway (645288); Crosslinking Of Collagen Fibrils Pathway (730308); Extracellular Matrix Organization Pathway (576262)

ncbi summary :

Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity. [provided by RefSeq, Jul 2008]

uniprot summary :

PCOLCE: Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity. Protein type: Extracellular matrix; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 7q22. Cellular Component: extracellular matrix; extracellular space. Molecular Function: heparin binding; collagen binding; protein binding; protease activator activity. Biological Process: multicellular organismal development; proteolysis

size1 :

0.01 mg

price1 :

135 USD

size2 :

0.05 mg

price2 :

230

size3 :

0.1 mg

price3 :

310

more info or order :

MyBioSource product webpage