catalog number :
MBS2004207
products full name :
Biotin-Linked Antibody to Regenerating Islet Derived Protein 3 Alpha (REG3a)
products short name :
Regenerating Islet Derived Protein 3 Alpha (REG3a)
other names :
regenerating islet-derived protein 3-alpha; Regenerating islet-derived protein 3-alpha; regenerating islet-derived protein 3-alpha; REG-3-alpha; reg III-alpha; PAP homologous protein; human proislet peptide; pancreatitis-associated protein 1; proliferation-inducing protein 34; proliferation-inducing protein 42; hepatocarcinoma-intestine-pancreas; pancreatic beta cell growth factor; hepatointestinal pancreatic protein; regenerating islet-derived protein III-alpha; regenerating islet-derived 3 alpha; Hepatointestinal pancreatic protein; HIP/PAP; Human proislet peptide; Pancreatitis-associated protein 1; Regenerating islet-derived protein III-alpha
products gene name :
REG3a
other gene names :
REG3A; REG3A; HIP; PAP; PAP1; REG3; INGAP; PAP-H; PBCGF; HIP/PAP; REG-III; HIP; PAP; PAP1; REG-3-alpha; HIP/PAP
uniprot entry name :
REG3A_HUMAN
sequence :
Sequence: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSGSEF-C PKGSKAYGSH CYALFLSPKS WTDADLACQK RPSGNLVSVL SGAEGSFVSS LVKSIGNSYS YVWIGLHDPT QGTEPNGEGW EWSSSDVMNY FAWERNPSTI SSPGHCASLS RSTAFLRWKD YNCN
specificity :
The antibody is a rabbit polyclonal antibody raised against REG3a conjugated to biotin. It has been selected for its ability to recognize REG3a in Immunohistochemical staining and Western blotting.
purity :
Affinity Chromatography
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
storage stability :
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
tested application :
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB), ICC, IHC-P, IHC-F, ELISA
app notes :
Western blotting: 1:100-400. Immunocytochemistry in formalin fixed cells: 1:100-500. Immunohistochemistry in formalin fixed frozen section: 1:100-500. Immunohistochemistry in paraffin section: 1:50-200. Enzyme-linked Immunosorbent Assay: 1:100-200
other info2 :
Conjugation: Biotin. Form & Buffer: Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol. Immunogen: REG3a, Human
products categories :
Biotin Antibody
products description :
Recombinant REG3a (Cys40~Asn164) expressed in E.coli.
ncbi acc num :
NP_002571.1
ncbi gb acc num :
NM_002580.2
ncbi mol weight :
19,395 Da
ncbi summary :
This gene encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this gene is observed during pancreatic inflammation and liver carcinogenesis. The mature protein also functions as an antimicrobial protein with antibacterial activity. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Nov 2014]
uniprot summary :
REG3A: Might be a stress protein involved in the control of bacterial proliferation. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 2p12. Cellular Component: extracellular space; cytoplasm. Molecular Function: carbohydrate binding. Biological Process: heterophilic cell adhesion; cell proliferation; multicellular organismal development; negative regulation of keratinocyte differentiation; acute-phase response