Polyclonal Antibody to Oncostatin M (OSM) | MyBioSource MBS2003922 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Oncostatin M (OSM)

catalog :

MBS2003922

quantity :

0.01 mg

price :

105 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Recombinant OSM, Mouse.

image 2 :

DAB staining on IHC-P; . Samples: Mouse Stomach Tissue;. Primary Ab: 20ug/ml Rabbit Anti-Mouse OSM Antibody. Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (MBS2086047)

image 3 :

DAB staining on IHC-P;. Samples: Mouse Uterus Tissue;. Primary Ab: 20ug/ml Rabbit Anti-Mouse OSM Antibody. Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047)

product information

catalog number :

MBS2003922

products type :

Antibody

products full name :

Polyclonal Antibody to Oncostatin M (OSM)

products short name :

[Oncostatin M (OSM)]

other names :

[oncostatin-M; Oncostatin-M; oncostatin-M; oncostatin M]

products gene name :

[OSM]

other gene names :

[Osm; Osm; OncoM; OSM]

clonality :

Polyclonal

host :

Rabbit

purity :

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

form :

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

concentration :

0.86mg/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

app notes :

Western blotting: 0.5-2ug/mL;1:430-1700. Immunohistochemistry: 5-20ug/mL;1:43-170. Immunocytochemistry: 5-20ug/mL;1:43-170. Optimal working dilutions must be determined by end user.

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

image3 heading :

Immunohistochemistry (IHC)

other info1 :

Organism Species: Mus musculus (Mouse). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant OSM (Lys116~Arg205 (Accession # P53347)) expressed in E.coli

other info2 :

Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2037935

ncbi gi num :

61656173

ncbi acc num :

NP_001013383.1

ncbi gb acc num :

NM_001013365.2

uniprot acc num :

P53347

ncbi pathways :

Adipogenesis Pathway (198299); Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); Jak-STAT Signaling Pathway (83274); Jak-STAT Signaling Pathway (488); PI3K-Akt Signaling Pathway (692242); PI3K-Akt Signaling Pathway (692979)

uniprot summary :

OSM: Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration. Belongs to the LIF/OSM family. Protein type: Cytokine; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 11 A1 11 2.94 cM. Cellular Component: extracellular region; extracellular space. Molecular Function: cytokine activity; growth factor activity; oncostatin-M receptor binding. Biological Process: behavioral response to pain; immune response; negative regulation of cell proliferation; negative regulation of hormone secretion; negative regulation of meiotic nuclear division; peripheral nervous system development; positive regulation of cell proliferation; positive regulation of MAPK cascade; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of tyrosine phosphorylation of STAT protein; regulation of growth; response to heat; tyrosine phosphorylation of STAT protein

size1 :

0.01 mg

price1 :

105 USD

size2 :

0.02 mg

price2 :

125

size3 :

0.05 mg

price3 :

170

size4 :

0.1 mg

price4 :

210

size5 :

0.2 mg

price5 :

315

size6 :

1 mg

price6 :

745

more info or order :

MyBioSource product webpage