catalog number :
MBS2003918
products full name :
Polyclonal Antibody to Defensin Beta 1 (DEFb1)
products short name :
[Defensin Beta 1 (DEFb1)]
other names :
[beta-defensin 1; Beta-defensin 1; beta-defensin 1; defensin beta 1; Defensin, beta 1]
products gene name :
[DEFb1]
other gene names :
[Defb1; Defb1; CDK4; BD-1; rBD-1]
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol
concentration :
0.55 mg/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP.
app notes :
Western blotting: 0.5-2 ug/mL;1:270-1100. Immunohistochemistry: 5-20 ug/mL;1:27-110. Immunocytochemistry: 5-20 ug/mL;1:27-110. Optimal working dilutions must be determined by end user
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Organism Species: Rattus norvegicus (Rat). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant DEFb1 (Ala22~Ser69 (Accession # O89117)) expressed in E.coli
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2054519
ncbi acc num :
NP_113998.1
ncbi gb acc num :
NM_031810.1
ncbi pathways :
Beta Defensins Pathway (1121596); Defensins Pathway (1121594); Immune System Pathway (1121507); Innate Immune System Pathway (1121536)
ncbi summary :
cationic peptides with broad-spectrum antimicrobial activity; may mediate mucosal defenses of several organs [RGD, Feb 2006]
uniprot summary :
defensin, beta 1: Has bactericidal activity. Belongs to the beta-defensin family. Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 16q12.5. Cellular Component: extracellular space; extrinsic component of membrane; intracellular. Molecular Function: CCR6 chemokine receptor binding; identical protein binding. Biological Process: acute inflammatory response; antibacterial humoral response; cAMP-mediated signaling; defense response to bacterium; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; innate immune response; innate immune response in mucosa; response to bacterium; response to testosterone stimulus