product summary
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company name :
MyBioSource
product type :
antibody
product name :
Polyclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10)
catalog :
MBS2003763
quantity :
0.05 mg
price :
280 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2003763
products type :
Antibody
products full name :
Polyclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10)
products short name :
A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10)
other names :
A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 1 preproprotein; A disintegrin and metalloproteinase with thrombospondin motifs 10; A disintegrin and metalloproteinase with thrombospondin motifs 10; ADAM-TS 10; zinc metalloendopeptidase; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 10; ADAM metallopeptidase with thrombospondin type 1 motif, 10
products gene name :
ADAMTS10
other gene names :
ADAMTS10; ADAMTS10; WMS; WMS1; ADAM-TS10; ADAMTS-10; ADAM-TS 10; ADAM-TS10; ADAMTS-10
uniprot entry name :
ATS10_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Rat
sequence length :
1103
specificity :
The antibody is a rabbit polyclonal antibody raised against ADAMTS10. It has been selected for its ability to recognize ADAMTS10 in immunohistochemical staining andwestern blotting.
purity :
Affinity Chromatography
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
concentration :
200ug/ml
storage stability :
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
tested application :
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
app notes :
Western blotting: 1:100-400. Immunocytochemistry in formalin fixed cells: 1:100-500. Immunohistochemistry in formalin fixed frozen section: 1:100-500. Immunohistochemistry in paraffin section: 1:50-200. Enzyme-linked Immunosorbent Assay: 1:100-200
ncbi gi num :
537544566
ncbi acc num :
NP_112219.3
ncbi gb acc num :
NM_030957.3
uniprot acc num :
Q9H324
ncbi mol weight :
120,874 Da
ncbi summary :
This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008]
uniprot summary :
ADAMTS10: Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues. Defects in ADAMTS10 are the cause of Weill-Marchesani syndrome 1 (WMS1). WMS1 is a rare connective tissue disorder characterized by short stature, brachydactyly, joint stiffness, and eye abnormalities including microspherophakia, ectopia lentis, severe myopia and glaucoma. Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Protease; Secreted; EC 3.4.24.-. Chromosomal Location of Human Ortholog: 19p13.2. Cellular Component: extracellular matrix; microfibril. Molecular Function: protein binding; zinc ion binding; metalloendopeptidase activity. Biological Process: proteolysis. Disease: Weill-marchesani Syndrome 1
size1 :
0.05 mg
price1 :
280 USD
size2 :
0.1 mg
price2 :
385
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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