Polyclonal Antibody to Interleukin 10 Receptor Beta (IL10Rb) | MyBioSource MBS2003603 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Interleukin 10 Receptor Beta (IL10Rb)

catalog :

MBS2003603

quantity :

0.01 mg

price :

110 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Recombinant protein.

image 2 :

DABstainingonIHC-P.Samples:MouseTissue)

product information

catalog number :

MBS2003603

products type :

Antibody

products full name :

Polyclonal Antibody to Interleukin 10 Receptor Beta (IL10Rb)

products short name :

[Interleukin 10 Receptor Beta (IL10Rb)]

other names :

[Interleukin-10 receptor subunit beta; Interleukin-10 receptor subunit beta; interleukin-10 receptor subunit beta; interleukin 10 receptor, beta; Cytokine receptor class-II member 4; Cytokine receptor family 2 member 4; CRF2-4; Interleukin-10 receptor subunit 2; IL-10R subunit 2; IL-10R2; CD_antigen: CDw210b]

products gene name :

[IL10Rb]

other gene names :

[Il10rb; Il10rb; Crfb4; CRF2-4; Il10r2; D21S58h; IL-10R2; AI528744; D16H21S58; 6620401D04Rik; Crfb4; IL-10 receptor subunit beta; IL-10R subunit beta; IL-10RB; CRF2-4; IL-10R subunit 2; IL-10R2]

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

purity :

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

form :

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

concentration :

1 mg/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

WB; IHC; ICC; IP.

app notes :

Western blotting: 0.5-2 ug/mL;1:500-2000. Immunohistochemistry: 5-20 ug/mL;1:50-200. Immunocytochemistry: 5-20 ug/mL;1:50-200. Optimal working dilutions must be determined by end user.

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

other info1 :

Immunogen: Recombinant IL10Rb (Val42~Thr218) expressed in E.coli.

other info2 :

Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2057346

ncbi gi num :

10720037

ncbi acc num :

Q61190.1

uniprot acc num :

Q61190

ncbi pathways :

Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); Epstein-Barr Virus Infection Pathway (585576); Epstein-Barr Virus Infection Pathway (587115); Jak-STAT Signaling Pathway (83274); Jak-STAT Signaling Pathway (488); Toxoplasmosis Pathway (169644); Toxoplasmosis Pathway (169493); Tuberculosis Pathway (213781); Tuberculosis Pathway (213743)

uniprot summary :

IL10RB: Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IL29. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25). It is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints. Belongs to the type II cytokine receptor family. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 16 C3.3 16 52.87 cM. Cellular Component: integral component of membrane; membrane; plasma membrane. Molecular Function: interleukin-10 receptor activity; protein binding. Biological Process: defense response to virus

size1 :

0.01 mg

price1 :

110 USD

size2 :

0.02 mg

price2 :

125

size3 :

0.05 mg

price3 :

175

size4 :

0.1 mg

price4 :

225

size5 :

0.2 mg

price5 :

330

size6 :

1 mg

price6 :

785

more info or order :

MyBioSource product webpage