catalog number :
MBS2003092
products full name :
Polyclonal Antibody to Apolipoprotein D (APOD)
products short name :
[Apolipoprotein D (APOD)]
other names :
[apolipoprotein D; Apolipoprotein D; apolipoprotein D; apolipoprotein D]
products gene name :
[APOD]
other gene names :
[APOD; APOD; Apo-D; ApoD]
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as slution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol.
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropiate storage condition.
tested application :
WB; IHC; ICC; IP.
app notes :
Western blotting: 0.5-2 Ug/mL;1:500-2000. Immunohistochemistry: 5-20 Ug/mL;1:50-200. Immunocytochemistry: 5-20 Ug/mL;1:50-200. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Organism Species: Homo sapiens (Human). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant APOD (Gln21~Ser189) expressed in E.coli
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2061246
ncbi acc num :
NP_001638.1
ncbi gb acc num :
NM_001647.3
ncbi pathways :
Orphan Transporters Pathway (1127546); SLC-mediated Transmembrane Transport Pathway (119558); Transmembrane Transport Of Small Molecules Pathway (106572); Transport Of Fatty Acids Pathway (187185); Transport Of Vitamins, Nucleosides, And Related Molecules Pathway (161075)
ncbi summary :
This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism. [provided by RefSeq, Aug 2008]
uniprot summary :
APOD: APOD occurs in the macromolecular complex with lecithin- cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts. Belongs to the calycin superfamily. Lipocalin family. Protein type: Lipid-binding; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 3q29. Cellular Component: cell soma; dendrite; endoplasmic reticulum; extracellular region; extracellular space; perinuclear region of cytoplasm. Molecular Function: cholesterol binding; lipid transporter activity; protein binding. Biological Process: aging; angiogenesis; axon regeneration in the peripheral nervous system; brain development; glucose metabolic process; lipid metabolic process; lipid transport; negative regulation of focal adhesion assembly; negative regulation of protein import into nucleus; negative regulation of smooth muscle cell proliferation; response to axon injury; response to drug; response to reactive oxygen species; tissue regeneration