product summary
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company name :
MyBioSource
product type :
antibody
product name :
Polyclonal Antibody to Cytochrome C, Somatic (CYCS)
catalog :
MBS2002987
quantity :
0.05 mg
price :
275 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2002987
products type :
Antibody
products full name :
Polyclonal Antibody to Cytochrome C, Somatic (CYCS)
products short name :
Cytochrome C, Somatic (CYCS)
other names :
Cytochrome c, somatic; Cytochrome c; cytochrome c; cytochrome c, somatic
products gene name :
CYCS
other gene names :
CYCS; CYCS; CYC; HCS; THC4; CYC
uniprot entry name :
CYC_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Porcine
specificity :
The antibody is a rabbit polyclonal antibody raised against CYCS. It has been selected for its ability to recognize CYCS in immunohistochemical staining and western blotting.
purity :
Affinity Chromatography
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
concentration :
200ug/ml
storage stability :
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
tested application :
Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Parafin, ELISA (EIA), Western Blot (WB)
app notes :
Western blotting: 1:50-400. Immunocytochemistry in formalin fixed cells: 1:50-500. Immunohistochemistry in formalin fixed frozen section: 1:50-500. Immunohistochemistry in paraffin section: 1:10-100. Enzyme-linked Immunosorbent Assay: 1:100-200. Optimal working dilutions must be determined by end user.
ncbi gi num :
45501024
ncbi acc num :
AAH67222.1
uniprot acc num :
P99999
ncbi pathways :
AGE/RAGE Pathway (698754); Activation Of Caspases Through Apoptosome-mediated Cleavage Pathway (105672); Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Alzheimers Disease Pathway (672448); Amyotrophic Lateral Sclerosis (ALS) Pathway (83099); Amyotrophic Lateral Sclerosis (ALS) Pathway (511); Apoptosis Pathway (198797); Apoptosis Pathway (83060); Apoptosis Pathway (470)
ncbi summary :
This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.[provided by RefSeq, Jul 2010]
uniprot summary :
CYCS: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Belongs to the cytochrome c family. Protein type: Oxidoreductase; Apoptosis; Protein phosphatase, Ser/Thr (non-receptor); Mitochondrial. Chromosomal Location of Human Ortholog: 7p15.3. Cellular Component: protein phosphatase type 2A complex; mitochondrion; mitochondrial inner membrane; mitochondrial intermembrane space; nucleus; cytosol. Molecular Function: electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity; protein binding; iron ion binding; heme binding; protein serine/threonine phosphatase activity. Biological Process: cellular metabolic process; mitochondrion organization and biogenesis; response to reactive oxygen species; dephosphorylation; apoptosis; organelle organization and biogenesis; cellular respiration; mitochondrial electron transport, cytochrome c to oxygen; caspase activation via cytochrome c; DNA fragmentation during apoptosis; transmembrane transport; mitochondrial electron transport, ubiquinol to cytochrome c. Disease: Thrombocytopenia 4
size1 :
0.05 mg
price1 :
275 USD
size2 :
0.1 mg
price2 :
385
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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