Polyclonal Antibody to Connective Tissue Growth Factor (CTGF) | MyBioSource MBS2002874 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Connective Tissue Growth Factor (CTGF)

catalog :

MBS2002874

quantity :

0.01 mg

price :

115 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

sheep

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Ovine Brain Tissue.

image 2 :

Western Blot: Sample: Recombinant CTGF, Ovine.

product information

catalog number :

MBS2002874

products type :

Antibody

products full name :

Polyclonal Antibody to Connective Tissue Growth Factor (CTGF)

products short name :

[Connective Tissue Growth Factor (CTGF)]

other names :

[connective tissue growth factor; Connective tissue growth factor; connective tissue growth factor; Connective tissue growth factor]

products gene name :

[CTGF]

other gene names :

[CTGF]

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Sheep

sequence length :

349

sequence :

Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF- APCVFGGTVY RSGESFQSSC KYQCTCLDGS VGCVPLCSVD IRLPSPDCPF PRRVKLPGKC CEEWVCDEPK EHTVVGPALA AYRPEDTFGP DPTMIRANCL VQTTEWSACS KTCGMGISTR VTNDNAFCRL EKQSRLCMVR PCEADLEENI KKGKKCIRTP KISKPIKFEL SGCTSMKTYR AKFCGVCTDG RCCTPHRTTT LPVEFKCPDG EVMKKSMMFI KTCACHYNCP

specificity :

The antibody is a rabbit polyclonal antibody raised against CTGF. It has been selected for its ability to recognize CTGF in immunohistochemical staining andwestern blotting.

purity :

Antigen-specific Affinity Chromatography

form :

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

concentration :

200ug/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM.

app notes :

Western blotting: 0.5-2ug/ml. Immunocytochemistry in formalin fixed cells: 5-20ug/ml. Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml. Immunohistochemistry in paraffin section: 5-20ug/ml. Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml. Optimal working dilutions must be determined by end user.

image1 heading :

Western Blot (WB)

image2 heading :

Western Blot (WB)

other info1 :

Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant CTGF (Ala101~Pro330) expressed in E.coli.

other info2 :

Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2034982

ncbi gi num :

257900455

ncbi acc num :

NP_001158186.1

ncbi gb acc num :

NM_001164714.1

uniprot acc num :

C7EDS5

ncbi mol weight :

37,966 Da

ncbi summary :

The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009]

uniprot summary :

CTGF: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Belongs to the CCN family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cell adhesion; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 6q23.1. Cellular Component: Golgi apparatus; proteinaceous extracellular matrix; extracellular space; cis-Golgi network; intracellular membrane-bound organelle; perinuclear region of cytoplasm; plasma membrane; extracellular region; cell cortex; cytosol. Molecular Function: heparin binding; integrin binding; insulin-like growth factor binding; protein binding; growth factor activity; fibronectin binding. Biological Process: response to peptide hormone stimulus; epidermis development; response to anoxia; cell-matrix adhesion; positive regulation of collagen biosynthetic process; positive regulation of JNK cascade; positive regulation of caspase activity; cellular lipid metabolic process; response to estradiol stimulus; cell-cell signaling; positive regulation of stress fiber formation; positive regulation of cell proliferation; tissue homeostasis; response to wounding; response to glucose stimulus; angiogenesis; regulation of cell growth; cell adhesion; cell differentiation; positive regulation of cell activation; cartilage condensation; integrin-mediated signaling pathway; transcription initiation from RNA polymerase II promoter; cell migration; ossification; fibroblast growth factor receptor signaling pathway; organ senescence; response to mineralocorticoid stimulus; response to amino acid stimulus; gene expression; positive regulation of protein amino acid phosphorylation; regulation of chondrocyte differentiation; positive regulation of cell differentiation; lung development

size1 :

0.01 mg

price1 :

115 USD

size2 :

0.02 mg

price2 :

135

size3 :

0.05 mg

price3 :

195

size4 :

0.1 mg

price4 :

255

size5 :

0.2 mg

price5 :

390

size6 :

1 mg

price6 :

925

more info or order :

MyBioSource product webpage