catalog number :
MBS2002719
products full name :
Biotin-Linked Antibody to Surfactant Associated Protein D (SPD)
products short name :
[Surfactant Associated Protein D (SPD)]
other names :
[Surfactant associated protein D; Pulmonary surfactant-associated protein D; pulmonary surfactant-associated protein D; PSP-D; lung surfactant protein D; surfactant associated protein D; Lung surfactant protein D]
products gene name :
[SPD]
other gene names :
[Sftpd; Sftpd; SP-D; Sftp4; AI573415; Sftp4; PSP-D; SP-D]
uniprot entry name :
SFTPD_MOUSE
reactivity :
Mus musculus (Mouse)
specificity :
The antibody is a rabbit polyclonal antibody raised against SPD conjugated to biotin. It has been selected for its ability to recognize SPD in immunohistochemical staining andwestern blotting.
purity :
Antigen-specific Affinity Chromatography.
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4oC for frequent use. Aliquot and store at -20oC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37oC for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC.
app notes :
Western blotting: 0.5-2ug/mL. Immunohistochemistry: 5-20ug/mL. Immunocytochemistry: 5-206ug/mL. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot
other info1 :
Source: Antibody labeling. Label: Biotin. Traits: Liquid. Immunogen: Recombinant SPD (Gly45~Pro221) expressed in E.coli.
other info2 :
Unconjugated Antibody: The unconjugated antibody version of this item is also available as catalog #MBS2005146
products categories :
Biotin Antibody
ncbi acc num :
AAH03705.1
ncbi pathways :
Phagosome Pathway (153914); Phagosome Pathway (153859)
uniprot summary :
SFTPD: Contributes to the lung s defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. Belongs to the SFTPD family. Protein type: Secreted, signal peptide; Secreted. Cellular Component: multivesicular body; proteinaceous extracellular matrix; extracellular space; collagen; rough endoplasmic reticulum; cytoplasm; extracellular region; cytoplasmic vesicle. Molecular Function: monosaccharide binding; identical protein binding; lipopolysaccharide binding; carbohydrate binding. Biological Process: negative regulation of phagocytosis; negative regulation of T cell proliferation; immune system process; positive regulation of phagocytosis; innate immune response; regulation of liquid surface tension; opsonization; respiratory gaseous exchange; surfactant homeostasis; alveolus development; negative regulation of interleukin-2 production