Polyclonal Antibody to Cholecystokinin (CCK) | MyBioSource MBS2002701 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Cholecystokinin (CCK)

catalog :

MBS2002701

quantity :

0.01 mg

price :

105 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Recombinant CCK, Mouse.

image 2 :

DAB staining on IHC-P; . Samples: Mouse Stomach Tissue.

product information

catalog number :

MBS2002701

products type :

Antibody

products full name :

Polyclonal Antibody to Cholecystokinin (CCK)

products short name :

[Cholecystokinin (CCK)]

other names :

[cholecystokinin isoform 2; Cholecystokinin; cholecystokinin; cholecystokinin]

products gene name :

[CCK]

other gene names :

[Cck; Cck; CCK; CCK33; CCK12; CCK8]

clonality :

polyclonal

host :

rabbit

purity :

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

form :

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

concentration :

0.48mg/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

app notes :

Western blotting: 0.5-2ug/mL. Immunohistochemistry: 5-20ug/mL. Immunocytochemistry: 5-20g/mL. Optimal working dilutions must be determined by end user.

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

other info1 :

Organism Species: Mus musculus (Mouse). Source: Polyclonal antibody preparation. Traits: Liquid

other info2 :

Immunogen: Recombinant CCK (Met1~Ser115 (Accession # P09240)) expressed in E.coli ( MBS2009882 )

ncbi gi num :

548962138

ncbi acc num :

NP_001271437.1

ncbi gb acc num :

NM_001284508.2

uniprot acc num :

P09240

ncbi pathways :

Class A/1 (Rhodopsin-like Receptors) Pathway (1367055); G Alpha (q) Signalling Events Pathway (1367088); GPCR Downstream Signaling Pathway (1367084); GPCR Ligand Binding Pathway (1367054); Gastrin-CREB Signalling Pathway Via PKC And MAPK (1367105); Peptide Ligand-binding Receptors Pathway (1367056); Signal Transduction Pathway (1366876); Signaling By GPCR Pathway (1367053)

ncbi summary :

This gene encodes a member of the gastrin/cholecystokinin family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the peptide hormones cholecystokinin-8, -12, -33, and others. The encoded peptides have been shown to regulate gastric acid secretion and food intake. A sulfated form of cholecystokinin-8 may modulate neuronal activity in the brain. Homozygous knockout mice for this gene exhibit impaired insulin secretion, enhanced insulin sensitivity, and resistance to obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]

uniprot summary :

CCK: This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. Belongs to the gastrin/cholecystokinin family. Protein type: Cell development/differentiation; Hormone; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 9 72.43 cM 9 F4. Cellular Component: axon; axon hillock; cell soma; dendrite; extracellular region; extracellular space; perikaryon; terminal bouton. Molecular Function: hormone activity; neuropeptide hormone activity; protein binding. Biological Process: activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptosis; axonogenesis; behavioral fear response; eating behavior; negative regulation of appetite; neuron migration; positive regulation of apoptosis; positive regulation of cell proliferation; positive regulation of glutamate secretion; positive regulation of mitochondrial depolarization; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of protein oligomerization; protein kinase C-activating G-protein coupled receptor signaling pathway; regulation of sensory perception of pain; release of cytochrome c from mitochondria

size1 :

0.01 mg

price1 :

105 USD

size2 :

0.02 mg

price2 :

125

size3 :

0.05 mg

price3 :

170

size4 :

0.1 mg

price4 :

210

size5 :

0.2 mg

price5 :

315

size6 :

1 mg

price6 :

745

more info or order :

MyBioSource product webpage