product summary
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company name :
MyBioSource
product type :
antibody
product name :
Biotin-Linked Antibody to Serum Amyloid P Component (SAP)
catalog :
MBS2002237
quantity :
0.1 mg
price :
235 USD
clonality :
polyclonal
host :
rabbit
conjugate :
biotin
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2002237
products type :
Antibody
products full name :
Biotin-Linked Antibody to Serum Amyloid P Component (SAP)
products short name :
[Serum Amyloid P Component (SAP)]
other names :
[serum amyloid P-component; Serum amyloid P-component; serum amyloid P-component; pentaxin-related; 9.5S alpha-1-glycoprotein; epididymis secretory sperm binding protein Li 92n; amyloid P component, serum; 9.5S alpha-1-glycoprotein]
products gene name :
[SAP]
other gene names :
[APCS; APCS; SAP; PTX2; HEL-S-92n; PTX2; SAP]
uniprot entry name :
SAMP_HUMAN
clonality :
Polyclonal
host :
Rabbit
purity :
Antigen-specific Affinity Chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol
concentration :
0.54mg/ml
storage stability :
Storage: . Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: . The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunofluorescence (IF).
app notes :
Western blotting: 0.5-2µg/mL. Immunohistochemistry: 5-20µg/mL. Immunocytochemistry: 5-20µg/mL. Optimal working dilutions must be determined by end user
other info1 :
Organism Species: Homo sapiens (Human). Source: Antibody labeling. Label: Biotin. Traits: Liquid. Immunogen: Recombinant SAP (His20~Val223) expressed in E.coli.
other info2 :
Unconjugated Antibody: The unconjugated antibody version of this item is also available as catalog #MBS2007033
products categories :
Biotin Antibody
ncbi gi num :
4502133
ncbi acc num :
NP_001630.1
ncbi gb acc num :
NM_001639.3
uniprot acc num :
P02743
ncbi pathways :
Amyloids Pathway (366238); Disease Pathway (530764)
ncbi summary :
The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008]
uniprot summary :
APCS: Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin. SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits. Belongs to the pentaxin family. Protein type: Secreted; Secreted, signal peptide; Chaperone. Chromosomal Location of Human Ortholog: 1q21-q23. Cellular Component: extracellular matrix; extracellular space; protein complex; extracellular region; nucleus. Molecular Function: complement component C1q binding; unfolded protein binding; virion binding; calcium ion binding; carbohydrate binding. Biological Process: protein folding; negative regulation of virion penetration into host cell; negative regulation of acute inflammatory response; acute-phase response; innate immune response; chaperone-mediated protein complex assembly; negative regulation of monocyte differentiation; negative regulation of viral reproduction
size1 :
0.1 mg
price1 :
235 USD
size2 :
0.2 mg
price2 :
350
size3 :
1 mg
price3 :
835
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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