Polyclonal Antibody to Heparan Sulfate Proteoglycan (HSPG) | MyBioSource MBS2002056 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Heparan Sulfate Proteoglycan (HSPG)

catalog :

MBS2002056

quantity :

0.01 mg

price :

105 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot; Sample: Recombinant HSPG, Human.

image 2 :

Western Blot; Sample:. Lane1: Human Serum. Lane2: Hela cell lysate. Lane3: HepG2 cell lysateu . Primary Ab: 1ug/ml Rabbit Anti-Human HSPG Antibody. u Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047)

image 3 :

DAB staining on IHC-P;. Samples: Human Prostate Tissue;. Primary Ab: 20ug/ml Rabbit Anti- Human HSPG Antibody. Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047)

product information

catalog number :

MBS2002056

products type :

Antibody

products full name :

Polyclonal Antibody to Heparan Sulfate Proteoglycan (HSPG)

products short name :

[Heparan Sulfate Proteoglycan (HSPG)]

other names :

[syndecan-2; Syndecan-2; syndecan-2; syndecan 2; Fibroglycan; Heparan sulfate proteoglycan core protein; HSPG; CD_antigen: CD362]

products gene name :

[HSPG]

other gene names :

[SDC2; SDC2; HSPG; CD362; HSPG1; SYND2; HSPG1; SYND2; HSPG]

clonality :

Polyclonal

host :

Rabbit

purity :

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

form :

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

concentration :

1mg/ml

storage stability :

Storage:. Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months. Stability Test:. The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

Western Blot (WB), Immunohistochemistry (IHC), Immunocytomechistry (ICC), Immunoprecipitation (IP).

app notes :

Western blotting: 0.5-2ug/mL. Immunohistochemistry: 5-20ug/mL. Immunocytochemistry: 5-20ug/mL. Optimal working dilutions must be determined by end user.

image1 heading :

Western Blot (WB)

image2 heading :

Western Blot (WB)

image3 heading :

Immunohistochemistry (IHC)

other info1 :

Organism Species: Homo sapiens (Human). Source: Polyclonal antibody preparation. Traits: Liquid

other info2 :

Immunogen: Recombinant HSPG (Glu19~Glu144) expressed in E.coli

ncbi gi num :

40548378

ncbi acc num :

NP_002989.2

ncbi gb acc num :

NM_002998.3

uniprot acc num :

P34741

ncbi pathways :

A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway (645305); Axon Guidance Pathway (105688); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway (645308); Defective B3GAT3 Causes JDSSDHD Pathway (1127588); Defective B4GALT1 Causes B4GALT1-CDG (CDG-2d) Pathway (1127592); Defective B4GALT7 Causes EDS, Progeroid Type Pathway (1127587); Defective CHST14 Causes EDS, Musculocontractural Type Pathway (1127591); Defective CHST3 Causes SEDCJD Pathway (1127590)

ncbi summary :

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008]

uniprot summary :

syndecan-2: a heparan sulfate proteoglycan type I membrane protein that belongs to the syndecan proteoglycan family. Preferentially expressed in cells of mesenchymal origin. Is tyrosine phosphorylated and forms a complex with EphB2 in mouse brain. Plays a role in mediating adhesion and proliferation of colon carcinoma cells. Protein type: Cell adhesion; Cell surface; Membrane protein, integral; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 8q22.1. Cellular Component: cell surface; endoplasmic reticulum lumen; extracellular matrix; Golgi lumen; integral component of membrane; lysosomal lumen; plasma membrane. Molecular Function: identical protein binding; PDZ domain binding; protein binding. Biological Process: bioluminescence; cell migration; cellular protein metabolic process; dendrite morphogenesis; ephrin receptor signaling pathway; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; glycosaminoglycan metabolic process; leukocyte migration; post-translational protein modification; regulation of dendrite morphogenesis; retinoid metabolic process

size1 :

0.01 mg

price1 :

105 USD

size2 :

0.02 mg

price2 :

125

size3 :

0.05 mg

price3 :

165

size4 :

0.1 mg

price4 :

210

size5 :

0.2 mg

price5 :

310

size6 :

1 mg

price6 :

725

more info or order :

MyBioSource product webpage