antibody

Biotin-Linked Antibody to Trefoil Factor 1 (TFF1)

MBS2002033

0.1 mg

375 USD

polyclonal

rabbit

biotin

western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

Antibody

Biotin-Linked Antibody to Trefoil Factor 1 (TFF1)

Trefoil Factor 1 (TFF1)

trefoil factor 1; Trefoil factor 1; trefoil factor 1; protein pS2; polypeptide P1.A; gastrointestinal trefoil protein pS2; breast cancer estrogen-inducible protein; breast cancer estrogen-inducible sequence; trefoil factor 1; Breast cancer estrogen-inducible protein; PNR-2; Polypeptide P1.A; hP1.A; Protein pS2

TFF1

TFF1; TFF1; pS2; BCEI; HPS2; HP1.A; pNR-2; D21S21; BCEI; PS2; hP1.A

TFF1_HUMAN

Polyclonal

IgG

Rabbit

Human

84

The target protein is fused with two N-terminal Tags, His-tag and GST-tag and its sequence is listed below. MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTLEV LFQGPLGSEF-MATMENKVIC ALVLVSMLAL GTLAEAQTET CTVAPRERQN CGFPGVTPSQ CANKGCCFDD TVRGVPWCFY PNTIDVPPEE ECEF

The antibody is a rabbit polyclonal antibody raised against TFF1 conjugated to biotin. It has been selected for its ability to recognize TFF1 in immunohistochemical staining andwestern blotting.

Affinity Chromatography

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.

200ug/ml

Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB), ICC, IHC-P, IHC-F

Western blotting: 1:100-400. Immunocytochemistry in formalin fixed cells: 1:100-500. Immunohistochemistry in formalin fixed frozen section: 1:100-500. Immunohistochemistry in paraffin section: 1:50-200. Enzyme-linked Immunosorbent Assay: 1:100-200

UOM: 100µg

Conjugation: Biotin. Immunogen: TFF1, Human . Accession No.: RPB049Hu01

Biotin Antibody

Recombinant TFF1 (Met1~Phe84) expressed in E.coli.

4507451

NP_003216.1

NM_003225.2

P04155

9,150 Da

FOXA1 Transcription Factor Network Pathway (137979); Integrated Pancreatic Cancer Pathway (711360)

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]

TFF1: Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 21q22.3. Cellular Component: extracellular space. Molecular Function: protein binding; growth factor activity. Biological Process: negative regulation of cell proliferation; response to peptide hormone stimulus; maintenance of gastrointestinal epithelium; digestion; carbohydrate metabolic process; cell differentiation; response to iron ion; response to estradiol stimulus

0.1 mg

375 USD