product summary
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company name :
MyBioSource
product type :
antibody
product name :
Biotin-Linked Antibody to Polymeric Immunoglobulin Receptor (PIGR)
catalog :
MBS2001987
quantity :
0.1 mg
price :
245 USD
clonality :
polyclonal
host :
rabbit
conjugate :
biotin
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry, enzyme immunoassay, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2001987 image 1
(Figure. Western Blot; Sample: Recombinant protein.)
product information
catalog number :
MBS2001987
products type :
Antibody
products full name :
Biotin-Linked Antibody to Polymeric Immunoglobulin Receptor (PIGR)
products short name :
[Polymeric Immunoglobulin Receptor (PIGR)]
other names :
[polymeric immunoglobulin receptor; Polymeric immunoglobulin receptor; polymeric immunoglobulin receptor; poly-Ig receptor; hepatocellular carcinoma associated protein TB6; hepatocellular carcinoma-associated protein TB6; polymeric immunoglobulin receptor; Hepatocellular carcinoma-associated protein TB6]
products gene name :
[PIGR]
other gene names :
[PIGR; PIGR; PIgR]
uniprot entry name :
PIGR_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Mouse
sequence length :
764
specificity :
The antibody is a rabbit polyclonal antibody raised against PIGR conjugated to biotin. It has been selected for its ability to recognize PIGR in immunohistochemical staining andwestern blotting.
purity :
Affinity Chromatography
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
concentration :
200ug/ml
storage stability :
Store at 4 degree C for frequent use. Stored at -20 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
tested application :
Immunohistochemistry-Frozen/Paraffin (IHC-F/P), ELISA (EIA), Western Blot (WB), Immunocytomchemistry (ICC)
app notes :
Western blotting: 1:50-400. Immunocytochemistry in formalin fixed cells: 1:50-500. Immunohistochemistry in formalin fixed frozen section: 1:50-500. Immunohistochemistry in paraffin section: 1:10-100. Enzyme-linked Immunosorbent Assay: 1:100-5000. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
products categories :
Biotin Antibody
ncbi gi num :
31377806
ncbi acc num :
NP_002635.2
ncbi gb acc num :
NM_002644.3
uniprot acc num :
P01833
ncbi mol weight :
83,284 Da
ncbi pathways :
IL4-mediated Signaling Events Pathway (137933); Integrated Breast Cancer Pathway (219801); Intestinal Immune Network For IgA Production Pathway (128760); Intestinal Immune Network For IgA Production Pathway (128670)
ncbi summary :
This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.[provided by RefSeq, Sep 2009]
uniprot summary :
PIGR: This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. Protein type: Receptor, misc.; Immunoglobulin superfamily; Membrane protein, integral. Chromosomal Location of Human Ortholog: 1q31-q41. Cellular Component: extracellular space; integral to plasma membrane; plasma membrane; receptor complex. Molecular Function: polymeric immunoglobulin receptor activity. Biological Process: epidermal growth factor receptor signaling pathway; retinal homeostasis; detection of chemical stimulus involved in sensory perception of bitter taste; immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor; receptor clustering. Disease: Iga Nephropathy, Susceptibility To, 1
size1 :
0.1 mg
price1 :
245 USD
size2 :
0.2 mg
price2 :
360
size3 :
1 mg
price3 :
860
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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