product summary
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company name :
MyBioSource
product type :
antibody
product name :
HPRT antibody (clone AT2G8)
catalog :
MBS200197
quantity :
0.05 ml
price :
240 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AT2G8
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS200197
products type :
Antibody
products full name :
HPRT antibody (clone AT2G8)
products short name :
HPRT
products name syn :
HGPRT; HGPRTase; HPRT; Hypoxanthine-guanine phosphoribosyltransferase HPRT 1; HPRT1; Hypoxanthine guanine phosphoribosyltransferase; Hypoxanthine phosphoribosyltransferase 1 (Lesch Nyhan syndrome); Hypoxanthine phosphoribosyltransferase 1.
other names :
hypoxanthine-guanine phosphoribosyltransferase; Hypoxanthine-guanine phosphoribosyltransferase; hypoxanthine-guanine phosphoribosyltransferase; HGPRTase; hypoxanthine phosphoribosyltransferase 1
products gene name :
HPRT
other gene names :
HPRT1; HPRT1; HPRT; HGPRT; HPRT; HGPRT; HGPRTase
uniprot entry name :
HPRT_HUMAN
clonality :
Monoclonal
isotype :
IgG1, k
clone :
AT2G8
host :
Mouse
reactivity :
Human
sequence length :
218
purity :
By protein-G affinity chromatography
form :
Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide
concentration :
1mg/ml
storage stability :
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
HPRT is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. HPRT, which acts as a catalyst in the reaction between guanine and phosphoribosyl pyrophosphate to form GMP, functions primarily to salvage purines from degraded DNA to renewed purine synthesis.
other info1 :
Antigen Species: Human. Clone: Anti-human HPRT mAb, clone AT2G8, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human HPRT protein. Immunogen: Recombinant human HPRT (1-218aa) purified from E Coli
products categories :
Signal Transduction
products description :
HPRT is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. HPRT, which acts as a catalyst in the reaction between guanine and phosphoribosyl pyrophosphate to form GMP, functions primarily to salvage purines from degraded DNA to renewed purine synthesis.
products references :
Sculley DG, et al. (1993). Hum. Genet. 90 (3): 195-207. Stout JT, Caskey CT (1986). Annu. Rev. Genet. 19: 127-48. Davidson BL, et al. (1991). Am. J. Hum. Genet. 48 (5): 951-8.
ncbi gi num :
4504483
ncbi acc num :
NP_000185
ncbi gb acc num :
NM_000194.2
ncbi mol weight :
24,579 Da
ncbi pathways :
Drug Metabolism - Other Enzymes Pathway 83033!!Drug Metabolism - Other Enzymes Pathway 428!!Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Nucleotides Pathway 106263!!Nucleotide Metabolism Pathway 198876!!Purine Metabolism Pathway 82944!!Purine Metabolism Pathway 106265!!Purine Metabolism Pathway 307!!Purine Salvage Pathway 106273
ncbi summary :
The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.[provided by RefSeq, Jun 2009]
size :
0.05 ml
price :
240 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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