catalog number :
MBS2001931
products full name :
Polyclonal Antibody to Liver Expressed Antimicrobial Peptide 2 (LEAP2)
products short name :
Liver Expressed Antimicrobial Peptide 2 (LEAP2)
other names :
liver-expressed antimicrobial peptide 2; Liver-expressed antimicrobial peptide 2; liver-expressed antimicrobial peptide 2; liver expressed antimicrobial peptide 2
products gene name :
LEAP2
other gene names :
LEAP2; LEAP2; LEAP-2; LEAP-2
uniprot entry name :
LEAP2_HUMAN
sequence :
The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below. MRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTLEV LFQGPLGSEF-SPIPEVSS AKRRPRRMTP FWRGVSLRPI GASCRDDSEC ITRLCRKRRC SLSVAQ
specificity :
The antibody is a rabbit polyclonal antibody raised against LEAP2. It has been selected for its ability to recognize LEAP2 in immunohistochemical staining andwestern blotting.
purity :
Affinity Chromatography
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
storage stability :
Store at 4 degree C for frequent use. Stored at -20 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
tested application :
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
app notes :
Western blotting: 1:50-400. Immunocytochemistry in formalin fixed cells: 1:50-500. Immunohistochemistry in formalin fixed frozen section: 1:50-500. Immunohistochemistry in paraffin section: 1:10-100. Enzyme-linked Immunosorbent Assay: 1:100-200. Optimal working dilutions must be determined by end user.
other info1 :
Immunogen: LEAP2, Human. Immunogen Information: Recombinant LEAP2 (Ser23~Gln76) with two N-terminal Tags, His-tag and GST-tag expressed in E.coli. Accession No.: RPH750Hu01
ncbi acc num :
NP_443203.1
ncbi gb acc num :
NM_052971.2
ncbi summary :
This gene encodes a cysteine-rich cationic antimicrobial peptide that is expressed predominantly in the liver. The mature peptide has activity against gram-positive bacteria and yeasts. [provided by RefSeq, Sep 2014]
uniprot summary :
LEAP2: Has an antimicrobial activity. Belongs to the LEAP2 family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 5q31.1. Cellular Component: extracellular region. Biological Process: defense response to bacterium