antibody

Polyclonal Antibody to Albumin (ALB)

MBS2001826

0.05 mg

165 USD

polyclonal

rabbit

nonconjugated

human, rat

western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay, immunohistochemistry - paraffin section

Antibody

Polyclonal Antibody to Albumin (ALB)

Albumin (ALB)

albumin; Serum albumin; serum albumin; albumin (32 AA); albumin (AA 34); growth-inhibiting protein 20; cell growth inhibiting protein 42; albumin

ALB

ALB; ALB; PRO0883; PRO0903; PRO1341

ALBU_HUMAN

Polyclonal

IgG

Rabbit

Rat

609

The antibody is a rabbit polyclonal antibody raised against ALB. It has been selected for its ability to recognize ALB in immunohistochemical staining andwestern blotting.

Affinity Chromatography

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.

200ug/ml

Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)

Western blotting: 1:100-400. Immunocytochemistry in formalin fixed cells: 1:100-500. Immunohistochemistry in formalin fixed frozen section: 1:100-500. Immunohistochemistry in paraffin section: 1:50-200. Enzyme-linked Immunosorbent Assay: 1:100-200

Immunogen: Native Protein ALB of Rat Plasma

178344

AAA98797.1

P02768

69,367 Da

Bile Acid And Bile Salt Metabolism Pathway 106144!!Binding And Uptake Of Ligands By Scavenger Receptors Pathway 771599!!FOXA2 And FOXA3 Transcription Factor Networks Pathway 137911!!HDL-mediated Lipid Transport Pathway 106158!!Hemostasis Pathway 106028!!Lipid Digestion, Mobilization, And Transport Pathway 106111!!Lipoprotein Metabolism Pathway 106156!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!Platelet Activation, Signaling And Aggregation Pathway 106034

Function: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca2+, Na+, K+, fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Ref.32. Subcellular location: Secreted. Tissue specificity: Plasma. Post-translational modification: Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.Glycated in diabetic patients.Phosphorylation sites are present in the extracellular medium.Acetylated on Lys-223 by acetylsalicylic acid. Ref.25. Polymorphism: A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood. The sequence shown is that of variant albumin A. Involvement in disease: Dysalbuminemic hyperthyroxinemia (DH) [MIM:103600]: A disorder characterized by abnormally elevated levels of total serum thyroxine (T4) in euthyroid patients. It is due to abnormal serum albumin that binds T4 with enhanced affinity.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.61 Ref.62 Ref.63 Ref.64. Sequence similarities: Belongs to the ALB/AFP/VDB family.Contains 3 albumin domains. Caution: A peptide arising from positions 166 to 174 was originally (Ref.23 and Ref.24) termed neurotensin-related peptide (NRP) or kinetensin and was thought to regulate fat digestion, lipid absorption, and blood flow. Sequence caution: The sequence AAF22034.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAF69644.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAG35503.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

0.05 mg

165 USD