product summary
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company name :
MyBioSource
product type :
antibody
product name :
AGXT antibody (AT2T4)
catalog :
MBS200170
quantity :
0.05 ml
price :
240 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AT2T4
reactivity :
human
application :
ELISA, immunocytochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS200170
products type :
Antibody
products full name :
AGXT antibody (AT2T4)
products short name :
AGXT
products name syn :
Serpin B5; Protease inhibitor 5; SERPINB5; alanine-glyoxylate aminotransferase; AGXT1; PH1; AGT; SPT; AGT1; oxalosis I; primary hyperoxaluria type 1; L-alanine: glyoxylate aminotransferase 1; serine:pyruvate aminotransferase; glycolicaciduria
other names :
serine--pyruvate aminotransferase; Serine--pyruvate aminotransferase; serine--pyruvate aminotransferase; L-alanine: glyoxylate aminotransferase 1; alanine--glyoxylate aminotransferase; hepatic peroxisomal alanine:glyoxylate aminotransferase; serine-pyruvate aminotransferase; serine:pyruvate aminotransferase; alanine-glyoxylate aminotransferase; Alanine--glyoxylate aminotransferase (EC:2.6.1.44); AGT
products gene name :
AGXT
other gene names :
AGXT; AGXT; AGT; PH1; SPT; AGT1; SPAT; TLH6; AGXT1; AGT1; SPAT; SPT; AGT
uniprot entry name :
SPYA_HUMAN
clonality :
Monoclonal
isotype :
IgG2b, k
clone :
AT2T4
host :
Mouse
reactivity :
Human
sequence length :
392
purity :
By protein-G affinity chromatography
form :
Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide
concentration :
1mg/ml
storage stability :
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
tested application :
ELISA (EIA), Immunofluorescence (IF)
app notes :
The antibody has been tested by ELISA and Immunofluorescence analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Immunofluorescence analysis is 1:500 ~ 1000. Recommended starting dilution is 1:500.
other info1 :
Antigen Species: Human. Clone: Anti-human AGXT mAb, clone AT2T4, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human AGXT protein. Immunogen: Recombinant AGXT (330-392aa) purified from E Coli
products categories :
Metabolism
products description :
The AGXT gene provides instructions for making a liver enzyme called alanine-glyoxylate aminotransferase. Inside liver cells, this enzyme is found in peroxisomes, structures that contain many different enzymes used to produce energy and the basic materials important for cellular activities. AGXT converts a compound called glyoxylate to glycine, an amino acid that is a building block for making enzymes and other proteins.
products references :
Donini S, et al., (2009) Biochem J 422(2):265-272 Grujic D, et al., (2009) Am J Nephrol 29(2):86-93 Williams EL, et al., (2009) Hum Mutat 30(6):910-917
ncbi gi num :
4557289
ncbi acc num :
NP_000021
ncbi gb acc num :
NM_000030.2
ncbi mol weight :
43,010 Da
ncbi pathways :
Alanine And Aspartate Metabolism Pathway 198783!!Alanine, Aspartate And Glutamate Metabolism Pathway 101142!!Alanine, Aspartate And Glutamate Metabolism Pathway 100063!!Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!Glycine, Serine And Threonine Metabolism Pathway 82949!!Glycine, Serine And Threonine Metabolism Pathway 313!!Glyoxylate And Dicarboxylate Metabolism Pathway 83002!!Glyoxylate And Dicarboxylate Metabolism Pathway 383!!Glyoxylate Metabolism Pathway 160990
ncbi summary :
This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. [provided by RefSeq, Jul 2008]
size :
0.05 ml
price :
240 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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