catalog number :
MBS2001655
products full name :
Polyclonal Antibody to N-Acylethanolamine Acid Amidase (NAAA)
products short name :
[N-Acylethanolamine Acid Amidase (NAAA)]
other names :
[N-acylethanolamine-hydrolyzing acid amidase isoform 2; N-acylethanolamine-hydrolyzing acid amidase; N-acylethanolamine-hydrolyzing acid amidase; N-acylethanolamine acid amidase; Acid ceramidase-like protein; N-acylsphingosine amidohydrolase-like; ASAH-like protein]
products gene name :
[NAAA]
other gene names :
[NAAA; NAAA; PLT; ASAHL; ASAHL; PLT; ASAH-like protein]
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
concentration :
0.38 mg/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP.
app notes :
Western blotting: 0.5-2) Ug/mL;1:190-750. Immunohistochemistry: 5-20)Ug/mL;1:19-75. Immunocytochemistry: 5-20)Ug/mL;1:19-75. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Organism Species: Homo sapiens (Human). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant NAAA (Asp112~Lys359) expressed in E.coli
ncbi acc num :
NP_001035861.1
ncbi gb acc num :
NM_001042402.1
ncbi summary :
This gene encodes an N-acylethanolamine-hydrolyzing enzyme which is highly similar to acid ceramidase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
ASAHL: Degrades bioactive fatty acid amides to their corresponding acids, with the following preference: N- palmitoylethanolamine N-myristoylethanolamine N- lauroylethanolamine = N-stearoylethanolamine N- arachidonoylethanolamine N-oleoylethanolamine. Also exhibits weak hydrolytic activity against the ceramides N- lauroylsphingosine and N-palmitoylsphingosine. Belongs to the acid ceramidase family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.5.1.-; Hydrolase. Chromosomal Location of Human Ortholog: 4q21.1. Cellular Component: cytoplasm; lysosomal lumen. Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; transcription factor binding. Biological Process: lipid metabolic process; neurotransmitter secretion